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Gelatin compound blood stopping liquid and preparation method thereof

A compound hemostatic and gelatin technology, applied in the field of medical materials, can solve the problems of difficult surgical incision and hemostasis, unpredictable and controllable curative effects, and ineffective hemostasis, and achieve the effects of reducing secondary damage and rapidly controlling bleeding

Inactive Publication Date: 2021-02-12
中国人民解放军联勤保障部队第九〇九医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current embolic agents given through the arterial route only have a significant effect on the control of arterial hemorrhage, and the capillary network and venous network hemorrhage caused by extensive contusions in the deep soft tissues of the retroperitoneum, pelvis, and thighs are still often clinical. The treatment is helpless, the existing compression method can not achieve the effect of hemostasis, surgical incision to stop bleeding is very difficult, and the curative effect is difficult to predict and control

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017]Preparation method of gelatin compound to stop blood; 1) Make gelatin, Yunnan Baiyao, and thrombin into powder with a particle size of less than 100 microns; 2) Mix the three raw materials in proportions (gelatin powder 1g, Yunnan Baiyao powder 1g, Hemagglutinin 1U), stored aseptically and dry.

Embodiment 2

[0019]Preparation method of gelatin compound to stop blood; 1) Make gelatin, Yunnan Baiyao, and thrombin into powder with a particle size of less than 100 microns; 2) Mix the three raw materials in proportions (gelatin powder 1.05g, Yunnan Baiyao powder 0.95) g, 1U hemagglutinin), aseptically and dry storage.

Embodiment 3

[0021]Preparation method of gelatin compound to stop blood; 1) Make gelatin, Yunnan Baiyao, and thrombin into powder with a particle size of less than 100 microns; 2) Mix the three raw materials in proportion (gelatin powder 0.95g, Yunnan Baiyao powder. 05g, 1U of hemagglutinin), stored aseptically and dry.

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PUM

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Abstract

The invention discloses gelatin compound antithrombotic blood and a preparation method thereof. The compound antithrombotic blood is prepared by mixing gelatin, Yunnan Baiyao and hemagglutinase. According to the blood stopping liquid, gelatin and hemagglutinase are taken as raw materials and Yunnan Baiyao as auxiliary materials, so on one hand, the hemostatic effect is prolonged, on the other hand, the blood stopping liquid has the effects of diminishing inflammation, diminishing swelling, promoting blood circulation, removing blood stasis and relieving pain, and later-period wound tissue rehabilitation is facilitated. Clinical tests prove that by applying the gelatin compound blood stopping liquid, embolism hemostasis at the capillary network level and the arteriovenous network level in awound tissue can be achieved, embolism is effectively targeted, the remaining functions of organs are protected, and the embolism effect at the arteriovenous level is superior to that of PVA and a micro-spring ring.

Description

Technical field[0001]The invention relates to the technical field of medical materials, in particular to a gelatin compound hemostatic agent and a preparation method thereof.Background technique[0002]For traumatic fractures or organ ruptures and hemorrhage, the current first-line treatment is to apply interventional techniques for intravascular embolization to stop bleeding. Interventional embolization methods for hemostasis have been more and more clinically recognized and recommended at home and abroad. Embolic materials include autologous blood clots (short-acting embolic agents), gelatin sponge (medium-acting embolic agents), PVA, coils, and colloidal adhesive embolic agents (long-acting embolic agents). However, the current embolization agent administered by the arterial route only has a significant effect on the control of arterial hemorrhage, and the capillary network and venous network bleeding caused by extensive contusion and laceration in the deep soft tissues of the retr...

Claims

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Application Information

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IPC IPC(8): A61L24/00A61L24/10A61K38/48A61K38/39A61K47/42A61P7/04A61K36/00
CPCA61K36/00A61K38/39A61K38/4833A61K47/42A61L24/0005A61L24/0015A61L24/104A61L2300/254A61L2300/30A61L2300/418A61L2400/04A61P7/04C12Y304/21005C08L89/00A61K2300/00
Inventor 欧阳林
Owner 中国人民解放军联勤保障部队第九〇九医院
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