Application of neutral polysaccharide from Brassica rapa L. in preparation of antioxidant drugs

A neutral polysaccharide and antioxidant technology, applied in the fields of drug combination, antidote, digestive system, etc., can solve the problems of neutral polysaccharide in turnips that have not been found in research, and achieve the enhancement of body stability, cell stability, delay effects of aging

Inactive Publication Date: 2021-03-09
XINJIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, no research has found the role of turnip neutral polysaccharide (BRNP) in anti-oxidation and anti-aging

Method used

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  • Application of neutral polysaccharide from Brassica rapa L. in preparation of antioxidant drugs
  • Application of neutral polysaccharide from Brassica rapa L. in preparation of antioxidant drugs
  • Application of neutral polysaccharide from Brassica rapa L. in preparation of antioxidant drugs

Examples

Experimental program
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Embodiment 1

[0026] Observation on the role of turnip neutral polysaccharide (BRNP) in anti-oxidation and aging.

[0027] 1. Materials and Instruments

[0028] Turnip neutral polysaccharide (BRNP) is obtained through laboratory preparation. For the specific preparation method, see patent CN107011453A. It should be noted that the alias of turnip is the Uyghur drug Chama;

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PUM

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Abstract

The invention relates to the technical field of application of neutral polysaccharide from Brassica rapa L., and particularly discloses application of the neutral polysaccharide from Brassica rapa L.in preparation of antioxidant drugs. Indexes in serum and whole brain and liver homogenate of mice in a D-galactose-induced aging mouse model and a control group are determined, respectively. It is found that the neutral polysaccharide from Brassica rapa L. has an antioxidant effect on the D-galactose-induced aging mouse model. The invention finds, for the first time, that the neutral polysaccharide from Brassica rapa L. significantly increases the activity of SOD, T-AOC, CAT, GSH and GSH-Px in serum and whole brain and liver homogenate, and significantly reduces the MDA content, thereby improving antioxidant ability and delaying senescence.

Description

technical field [0001] The invention relates to the technical field of application of turnip neutral polysaccharides, in particular to the use of turnip neutral polysaccharides in the preparation of antioxidant drugs. Background technique [0002] Turnip (Brassica rapa L.) is an alkaline plant with both medicinal and edible uses. In clinical use, it has the functions of nourishing yin and nourishing the lungs, invigorating the stomach and eliminating food, softening and facilitating urine, and eliminating excess body fluids. It has health care and preventive effects on lung and stomach diseases, and enhances physical fitness. Modern pharmacological studies have also found that turnip has the functions of anti-oxidation, anti-radiation, and prevention of cardiovascular diseases. [0003] Polysaccharides have the ability to load rich biological information and are the most abundant substances in natural products. Studies have shown that polysaccharides have the functions of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61K36/31A61P39/06A61P1/16A61P25/00
CPCA61K31/715A61K36/31A61P39/06A61P1/16A61P25/00
Inventor 海力茜·陶尔大洪常军民王小静马晓丽李欢欢周凯杨飞乔丽洁李亚童卡地尔亚·库尔班米合热尼沙·阿木热江阿吉然姆·阿布拉
Owner XINJIANG MEDICAL UNIV
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