Polypeptide microneedle and preparation method thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 宇肽生物(东莞)有限公司
- Publication Date
- 2021-04-13
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Abstract
Description
technical field
[0001] The invention belongs to the technical field of cosmetic polypeptides, and in particular relates to a polypeptide microneedle and a preparation method thereof. Background technique
[0002] Biologically active cosmetic peptides generally have 2 to 10 amino acid residues, a molecular weight of 100 to 2000, and are highly hydrophilic. The skin is relatively impermeable, and the stratum corneum of the skin is a multi-layered lipid bilayer formed by lipid molecules, with a dense structure and no blood vessels and lymphatic vessels, which prevents the transdermal absorption of water-soluble drugs and polymer lipophilic drugs. It is the main barrier for the transdermal absorption of functional ingredients. Therefore, the transport of some hydrophilic peptides on biomembranes is limited by their hydrophilicity and affected by the structure of biomembrane barriers. Although peptides have a high efficacy on skin remodeling, it is still difficult for some pept...