Optical fiber connection optical biological treatment window for rats

Abstract

The invention discloses an optical fiber connection optical biological treatment window for rats. The optical fiber connection optical biological treatment window comprises an optical fiber channel, an upper end plate and a lower end plate. The end part of the optical fiber extends into the optical fiber channel, and the optical fiber channel is detachably connected with the joint of the optical fiber; and the upper end plate and the lower end plate are fixedly connected to the two ends of the optical fiber channel respectively, the upper end plate is used for being fixedly connected with the skin through a suture line, the lower end plate is used for being fixedly connected with the paravertebral muscle through a suture line, and threading holes allowing the suture line to penetrate through are formed in the upper end plate and the lower end plate. Compared with the prior art, the optical fiber connection optical biological treatment window has the advantages that the effective dose of photobiological therapy reaching the spinal cord injury can be increased, frequent incision treatment does not need to be performed on the spine of the rat, and visual observation of the treatment process is facilitated.

Description

technical field [0001] The invention relates to the technical field of photobiotherapy devices, in particular to an optical fiber connection photobiotherapy window for rats. Background technique [0002] Spinal cord injury (SCI) is a worldwide problem. Its pathological process is divided into two stages: primary injury and secondary injury. The secondary immune and inflammatory response is the key link affecting the prognosis of SCI. There is no effective treatment for SCI. Clinically, surgical decompression and neurotrophy are the main treatments, but the treatment effect for severe injuries is not good; emerging treatment methods such as immunosuppressive drugs, cell transplantation, and biomaterials all have ethical issues , chemical toxicity and other deficiencies, can not be applied in clinical practice. [0003] Photobiomodulation therapy (Photobiomodulation, PBM) has been widely used in the clinical treatment of various diseases due to its clear anti-inflammatory eff...

AI Technical Summary

Problems solved by technology

Due to the deep position of the spinal cord tissue, the bone structure has a blocking effect on the laser light, and the skin and muscle tissue have serious scattering and absorption of light energy, so that the effective therapeutic dose of light energy cannot fully reach the surface of the spinal cord, resulting in inaccurate curative effect and severe Limiting the use of PBM in the treatment of SCI

[0005] In the past, in the photobiomodulation treatment model of spinal cord injury in rats, percutaneous irradiation or each opening of the incision was mainly used for irradiation. The way of percutaneous irradiation seriously affected the effective dose of photobiotherapy reaching the spinal cord injury. Exposure in a manner that can cause significant trauma

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