In-vitro detection system for intestinal migration compound motion and application thereof

A detection system and composite motion technology, applied in the field of neuroscience, can solve problems such as inconvenience of operation, loss of reagents, tissue damage, etc., and achieve the effects of prolonging survival time, accurate motion waveform, and high success rate
CN112710823APending Publication Date: 2021-04-27SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
Publication Date
2021-04-27

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Abstract

The invention provides an in-vitro detection system for intestinal migration compound motion and application thereof. The in-vitro detection system comprises a sample fixing device, a constant-temperature heater, a liquid storage cylinder, a peristaltic pump and a waste liquid collection cylinder, wherein the sample fixing device is positioned on the constant-temperature heater; the sample fixing device, the liquid storage cylinder and the peristaltic pump are connected through pipelines; the peristaltic pump is used for pumping liquid in the liquid storage cylinder into the sample fixing device through the liquid inlet pipe, and the liquid in the sample fixing device flows into the waste liquid collecting cylinder through the liquid outlet pipe. Tissues are kept active in an in-vitro state by adopting a mode of circularly heating and pouring a buffer solution, the in-vivo motion state of intestinal tracts is simulated to the greatest extent, and in-vitro detection of intestinal migration composite motion is realized by utilizing a video recording mode.
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Description

technical field

[0001] The invention belongs to the technical field of neuroscience, and relates to an in vitro detection system of intestinal migratory compound movement and its application. Background technique

[0002] As we all know, the gastrointestinal tract is the only way to absorb nutrients, and it is also an important organ that controls the balance of the body's internal environment. The gastrointestinal tract, on the one hand absorbs energy and nutrients from ingested food for use by the body, and on the other hand protects the body from toxins, pathogens, etc., and the coordination of these complex basic activities is largely dependent on the local nervous system To complete, the enteric nervous system (Enteric nervous system, ENS). ENS is the largest peripheral nervous system. It is a reticular nerve plexus structure composed of neurons and glial cells located in the intestinal wall, mainly including submucous plexus and myenteric plexus. The larger myenteric...

Claims

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