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Traditional Chinese medicine composition for treating osteoporosis as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve problems such as insufficient effect, achieve the effect of reducing content, reducing serum osteocalcin content, and alleviating the tendency of bone density reduction

Active Publication Date: 2021-06-18
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But overall, this simple supplement intervention is far from enough

Method used

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  • Traditional Chinese medicine composition for treating osteoporosis as well as preparation method and application thereof
  • Traditional Chinese medicine composition for treating osteoporosis as well as preparation method and application thereof
  • Traditional Chinese medicine composition for treating osteoporosis as well as preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] The Chinese medicine composition formula of the present embodiment is:

[0058] Rehmannia glutinosa 24g, Achyranthes bidentata 12g, Alisma 10g, Poria cocos 15g, Guizhi 10g, Achyranthes bidentata 12g, Clematis 15g, drynaria 15g, dog bone glue 10g (purchased from Shandong Dong'a Guojiaotang).

[0059] Based on the formula of the above-mentioned Chinese medicine composition, an oral Chinese medicine preparation for treating osteoporosis is prepared, and the specific preparation steps are as follows:

[0060] Weigh each component according to the formula of the traditional Chinese medicine composition of this embodiment, soak in clear water for 30 minutes, the amount of water soaked is advisable to submerge the medicine surface, boil with high fire (above 200°C), and use slow fire (100°C-200°C) after boiling. ) decoction for 30 minutes, pour out the liquid medicine. Then add hot water that has just submerged 3 cm of the medicinal residues into the medicinal residues, conti...

Embodiment 2

[0063] The Chinese medicine composition formula of the present embodiment is:

[0064] Rehmannia glutinosa 24g, Achyranthes bidentata 12g, Alisma 10g, Poria cocos 15g, Guizhi 10g, Achyranthes bidentata 12g, Clematis 15g, Sangji 15g, Drynaria 15g, dog bone glue 10g.

[0065] Based on the formula of the above-mentioned Chinese medicine composition, an oral Chinese medicine preparation for treating osteoporosis is prepared, and the specific preparation steps are as follows:

[0066] Weigh each component according to the formula of the traditional Chinese medicine composition of this embodiment, soak in clear water for 30 minutes, the amount of water soaked is advisable to submerge the medicine surface, boil with high fire (above 200°C), and use slow fire (100°C-200°C) after boiling. ) decoction for 30 minutes, pour out the liquid medicine. Then add hot water that has just submerged 3 cm of the medicinal residues into the medicinal residues, continue to decoct for 30 minutes, pou...

Embodiment 3

[0069] The Chinese medicine composition formula of the present embodiment is:

[0070] Rehmannia glutinosa 24g, Achyranthes bidentata 12g, Alisma 10g, Poria cocos 15g, Guizhi 10g, Achyranthes bidentata 12g, Clematis 15g, drynaria 15g, psoralen 15g, dog bone glue 10g.

[0071] Based on the formula of the above-mentioned Chinese medicine composition, an oral Chinese medicine preparation for treating osteoporosis is prepared, and the specific preparation steps are as follows:

[0072] Weigh each component according to the formula of the traditional Chinese medicine composition of this embodiment, soak in clear water for 30 minutes, the amount of water soaked is advisable to submerge the medicine surface, boil with high fire (above 200°C), and use slow fire (100°C-200°C) after boiling. ) decoction for 30 minutes, pour out the liquid medicine. Then add hot water that has just submerged 3 cm of the medicinal residues into the medicinal residues, continue to decoct for 30 minutes, p...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating osteoporosis as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises the following components: prepared rehmannia root, achyranthes root, radix cyathulae, rhizoma alismatis, poria cocos, cassia twig, radix clematidis, rhizoma drynariae and dog bone glue. The traditional Chinese medicine composition can relieve the trend of bone mineral density decrease, relieve calcium loss in serum or urine of an osteoporosis experimental subject, reduce the content of serum alkaline phosphatase (ALP), reduce the increased content of serum osteocalcin and reduce the expression of a bone resorption index I-type collagen cross-linked C-terminal peptide (CTX1), and has an excellent treatment effect on osteoporosis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating osteoporosis, a preparation method and application thereof. Background technique [0002] Osteoporosis (osteoporosis) is a metabolic bone disease, mainly caused by a variety of causes of decreased bone density and bone quality, bone microstructure damage, resulting in increased bone fragility, resulting in a systemic bone disease that is prone to fractures. Symptoms of osteoporosis fall into three main categories: pain, spinal deformation, and fractures. Pain itself can reduce the patient's quality of life. Spinal deformation and fractures can cause disability, restrict the patient's activities, and increase the incidence of lung infection and decubitus. A heavy economic burden on society. [0003] In related technologies, prevention is more important than treatment, and different treatment methods a...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61P19/10A61K35/32
CPCA61K36/804A61K36/21A61K36/884A61K36/076A61K36/54A61K36/716A61K36/126A61K35/32A61K36/185A61K36/487A61P19/10A61K2236/331A61K2300/00
Inventor 程发峰王雪茜王庆国
Owner BEIJING UNIV OF CHINESE MEDICINE