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Traditional Chinese medicine composition for treating chronic kidney diseases and chronic renal failure

A technology for chronic kidney disease and chronic renal failure, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as poor effect, and achieve the effect of significant clinical effect, good compliance, and good renal function.

Active Publication Date: 2021-06-18
SHANGHAI SEVENTH PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of treatment, modern medicine mainly uses diet control, blood pressure control, lipid lowering, lowering urine protein, correcting anemia and acid-base balance, and improving electrolyte imbalance for the treatment of early and middle stage renal insufficiency (CKD stage 3-4). , but it doesn't work well

Method used

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  • Traditional Chinese medicine composition for treating chronic kidney diseases and chronic renal failure

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Comparison scheme
Effect test

Embodiment 1

[0026] The traditional Chinese medicine composition for the treatment of chronic kidney disease and chronic renal failure of the present embodiment consists of the following raw materials in parts by weight: 10 parts of rhubarb, 30 parts of genus root, 30 parts of centella asiatica, 15 parts of curcuma, 30 parts of salvia miltiorrhiza 30 parts, 30 parts of smilax, 6 parts of safflower, 30 parts of Polygonum cuspidatum, 30 parts of deerbita, 30 parts of Ganoderma lucidum, 30 parts of astragalus and 10 parts of Citrus aurantium.

[0027] Luo, female, 67 years old, date of first visit: March 9, 2019.

[0028] History of present illness: The patient's physical examination 10 years ago found that the serum creatinine had increased to 121 μmol / L. No further examination was conducted to clarify the cause. He was only treated with Shenshuaining orally. He denied foamy urine and gross hematuria. Last year, there was nocturia increase, 2-3 times / day, so I went to the outpatient clinic o...

Embodiment 2

[0038] The traditional Chinese medicine composition for the treatment of chronic kidney disease and chronic renal failure of the present embodiment consists of the following raw materials in parts by weight: 8 parts of rhubarb, 35 parts of genus root, 25 parts of centella asiatica, 12 parts of curcuma, 32 parts , 25 parts of Smilax, 8 parts of safflower, 28 parts of Polygonum cuspidatum, 35 parts of Deerbitum, 26 parts of Ganoderma lucidum, 25 parts of Astragalus and 12 parts of Citrus aurantium.

[0039] Song, male, 40 years old. First consultation time: March 23, 2018

[0040] Chief complaint: cloudy urination, creatinine increased for 1 week.

[0041] History of present illness: The patient suffered from proteinuria 7 years ago and hematuria 2 years ago, all improved after symptomatic treatment. The patient has a history of hypertension for 10 years. He usually uses antihypertensive drugs to control blood pressure, and the control is good. A week ago, the patient develop...

Embodiment 3

[0048] The traditional Chinese medicine composition for the treatment of chronic kidney disease and chronic renal failure of the present embodiment is composed of the following raw materials in parts by weight: 12 parts of rhubarb, 25 parts of genus root, 35 parts of centella asiatica, 18 parts of curcuma, 28 parts of salvia miltiorrhiza 35 parts of smilax, 4 parts of safflower, 33 parts of Polygonum cuspidatum, 26 parts of deerbita, 33 parts of Ganoderma lucidum, 35 parts of astragalus and 8 parts of Citrus aurantium.

[0049] Dong Mou, female, 40 years old. First visit date: May 18, 2012

[0050] Chief complaint: creatinine continued to rise for 1 month.

[0051] History of present illness: The patient suffered from glomerular sclerosis in 2006, and the physical examination found that the creatinine was 414 μmol / L before January, so he came to see a doctor. In 2006, the patient went to a related hospital for proteinuria for a puncture examination, which showed glomerulonep...

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Abstract

The invention provides a traditional Chinese medicine composition for treating chronic kidney diseases and chronic renal failure. The traditional Chinese medicine composition is prepared from radix et rhizoma rhei preparata, Chinese peashrub roots, herba centellae, rhizoma curcumae, radix salviae miltiorrhizae, rhizoma smilacis glabrae, flos carthami, rhizoma polygoni cuspidati, herba pyrolae, lucid ganoderma, radix astragali and fructus aurantii. The radix et rhizoma rhei preparata has the effects of promoting blood circulation, detoxifying and eliminating turbidity, the Chinese peashrub roots has the effects of dispelling wind, detoxifying and reducring urinary protein, the herba centellae has the effects of dispelling wind, detoxifying and reducing creatinine, the rhizoma curcumae has the effects of breaking blood, promoting qi and resisting fibrosis, the radix salviae miltiorrhizae and the flos carthami have the effects of promoting blood circulation and removing blood stasis, the rhizoma smilacis glabrae has the effects of clearing heat, detoxifying and drying dampness, the rhizoma polygoni cuspidati has the effects of dispelling wind, detoxifying and reducing uric acid, the herba pyrolae has the effects of tonifying kidney and clearing away dieresis, the lucid ganoderma and the radix astragali have the effects of invigorating qi and strengthening health, and the fructus aurantii has the effects of soothing liver and regulating qi. The traditional Chinese medicine composition can effectively reduce proteinuria and hematuria of patients with chronic kidney diseases, relieve renal function progression of chronic renal failure, reduce serum creatinine, improve clinical symptoms of patients with chronic kidney diseases, especially chronic renal failure, and protect renal functions.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating chronic kidney disease and chronic renal failure. Background technique [0002] Chronic kidney disease (Chronic Kidney Disease, CKD) is a group of clinical syndromes that can be caused by various diseases. In recent years, its incidence and cost have increased year by year, and it is a new chronic disease that has endangered life. Chronic renal failure refers to the decline of glomerular filtration function and various complications caused by it. Chronic renal failure develops to end-stage renal disease (ESRD) and can only rely on replacement therapy (blood, peritoneal dialysis and kidney transplantation) to maintain life , but due to the limitations of cost, technology, trauma and other factors, it is difficult to popularize in our country at present, and even patients who have undergone renal replacem...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P13/12
CPCA61K36/708A61K36/48A61K36/23A61K36/9066A61K36/537A61K36/90A61K36/896A61K36/286A61K36/704A61K36/185A61K36/074A61K36/481A61K36/752A61P13/12A61K2300/00
Inventor 张传富叶景华路建饶
Owner SHANGHAI SEVENTH PEOPLES HOSPITAL
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