Traditional Chinese medicine composition as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine preparation, can solve the problems of ineffective treatment, cure of pharyngitis, recurrence and the like

Inactive Publication Date: 2021-08-24
INST OF CHINESE MATERIA MEDICA CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine treatment is mainly based on expelling wind and clearing heat, moistening lung and promoting phlegm, but most of them can only temporarily relieve the discomfort symptoms of pharyngitis. Type change to a different drug

Method used

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  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Alcohol extraction of Coptidis and Folium Folium, and other five-flavored medicines such as cicada slough: Weigh 45g of Coptidis and 60g of Folium Folium according to the recipe, add 6 times the amount of 70% ethanol to extract twice, filter the ethanol solution, and vacuum dry. Cicada slough 45g, golden buckwheat 60g, clam shell 120g, talc 120g, licorice 30g, add 8 times water to extract 2 times, water extract is concentrated and vacuum dried. Record it as 1# sample.

Embodiment 2

[0052] Alcohol extraction of coptis, golden buckwheat and Daqingye, and the rest of cicada slough and other four-flavored liquid extracts: 30g cicada slough, 80g sea clam, 80g talc, 20g licorice, add 8 times the amount of water to extract twice, concentrate the extract, and vacuum dry. Coptidis 30g, golden buckwheat 40g, Daqingye 40g, add 6 times the amount of 70% ethanol to extract twice, concentrate the ethanol solution, and vacuum dry. Recorded as 2# sample.

Embodiment 3

[0054] Coptis chinensis and other seven-flavor medicine extract: 30g cicada slough, 80g sea clam, 80g talc, 20g licorice, 30g coptis, 40g golden buckwheat, 40g Daqingye, add 8 times the amount of water to extract twice, concentrate the extract, and vacuum dry. Recorded as 3# sample.

[0055] Embodiment 1-3 is to take the pharmacodynamics and active ingredient of the chemical composition contained in all medicines of this product as index, carry out the selection of extraction process route, the result is as follows:

[0056] The content of index components berberine, glycyrrhizic acid and liquiritin were measured in the above samples respectively, and the results showed that the contents of index components in 1# and 2# samples were higher. The content of 3# sample is low, and the analysis reason may be that during the decoction process, berberine and glycyrrhizic acid combine to form a salt, which affects the dissolution of active ingredients.

[0057] Comparison of drug eff...

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Abstract

The invention discloses a traditional Chinese medicine composition and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine composition is prepared from, by weight, 1-5 parts of rhizoma coptidis, 1-5 parts of cicada slough, 2-7 parts of rhizoma fagopyri dibotryis, 2-7 parts of folium isatidis, 6-14 parts of clam shells, 6-14 parts of talc and 1-4 parts of liquorice.The traditional Chinese medicine composition is used for preparing a medicine for treating pharyngitis, and is suitable for acute attack of lung-stomach intrinsic heat type acute pharyngolaryngitis or chronic pharyngitis, has no adverse reaction and has a remarkable treatment effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition, a preparation method and an application thereof. Background technique [0002] Pharyngitis is inflammation of the pharyngeal mucosa, submucosal tissue, often as part of an upper respiratory tract infection. According to the length of the course of disease and the difference of pathological change character, be divided into acute pharyngitis, chronic pharyngitis two big classes. Acute pharyngitis can also be divided into acute simple pharyngitis, acute edematous pharyngitis and acute necrotizing pharyngitis 3 kinds, the most common with acute simple pharyngitis. Chronic pharyngitis is also divided into 3 types: chronic simple pharyngitis, chronic hypertrophic (or hypertrophic) pharyngitis, and chronic dry (or atrophic) pharyngitis. The pathological changes of the three have obvious differences. The ons...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/855A61K36/718A61P11/04A61K33/12A61K35/618A61K35/64
CPCA61K36/718A61K35/64A61K36/70A61K36/855A61K36/704A61K36/315A61K36/195A61K35/618A61K33/12A61K36/484A61P11/04A61K2236/331A61K2236/51A61K2236/333A61K2236/39A61K2300/00
Inventor 田纪祥赵晓昂金日显张东
Owner INST OF CHINESE MATERIA MEDICA CHINA ACAD OF CHINESE MEDICAL SCI
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