Whole-body-oriented three-dimensional magnetic particle imaging method, system and equipment

Abstract

The invention belongs to the technical field of magnetic particle imaging, particularly relates to a whole-body-oriented three-dimensional magnetic particle imaging method, a system and an equipment, and aims to solve the problem that whole-body imaging cannot be performed simultaneously during magnetic particle imaging. According to the invention, a single group of magnetic particle imaging systems are coupled to form an array type magnetic particle imaging system, and the imaging view is enlarged from a local part to a whole body size. In the signal acquisition process, excitation and receiving coils of each group of magnets in the whole body magnetic particle imaging system are synchronized, denoising and filtering amplification are carried out on obtained electromagnetic induction signals, image reconstruction is carried out by utilizing a deconvolution or regularization method, reconstructed images in all imaging view fields are spliced, finally, a three-dimensional distribution image of the magnetic particles in the whole body is obtained, whole-body imaging of an observed object is achieved, and high examination and diagnosis accuracy is achieved.

Description

technical field [0001] The invention belongs to the technical field of magnetic particle imaging, and in particular relates to a whole-body three-dimensional magnetic particle imaging method, system and equipment. Background technique [0002] In biomedical imaging detection, the non-invasive observation of the anatomical structure, functional metabolism and molecular cell activities of living organisms has always been a frontier research hotspot and development direction. Existing medical imaging technologies such as CT, MRI, SPECT, and optics have their own technical and application bottlenecks, such as optical imaging is limited by imaging depth, magnetic resonance imaging is limited by imaging sensitivity, and nuclide imaging is limited by ionizing radiation. and imaging resolution. Therefore, there is an urgent need for a new imaging technology with the characteristics of large depth, high sensitivity, and no radiation to meet the needs of in vivo imaging and precise q...

AI Technical Summary

Problems solved by technology

[0005] In order to solve the above-mentioned problems in the prior art, that is, in order to solve the problem that magnetic particle imaging cannot simultaneously image the whole body in the prior art, the first aspect of the present invention proposes a three-dimensional magnetic particle imaging method for the whole body, which includes the following step:

Images