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Flexible enzyme-free glucose sensor electrode and preparation method thereof

A glucose sensor, a flexible technology, applied in the direction of instruments, scientific instruments, and electrochemical variables of materials, etc., can solve the problems of difficult to effectively guarantee the conductivity and the decline of the catalytic performance of glucose, and achieve the guaranteed conductivity, high linearity, and improved sensing performance effect

Pending Publication Date: 2021-09-03
XI AN JIAOTONG UNIV
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Problems solved by technology

[0005] The purpose of the present invention is to overcome the above-mentioned shortcomings in the prior art that the electrodes of the existing flexible glucose sensor are difficult to effectively ensure the conductivity under bending and stretching states, and the catalytic performance of glucose is greatly reduced, and provide a flexible non-enzyme Glucose sensor electrode and preparation method thereof

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  • Flexible enzyme-free glucose sensor electrode and preparation method thereof
  • Flexible enzyme-free glucose sensor electrode and preparation method thereof
  • Flexible enzyme-free glucose sensor electrode and preparation method thereof

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Embodiment Construction

[0028] In order to enable those skilled in the art to better understand the solutions of the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only It is an embodiment of a part of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0029] It should be noted that the terms "first" and "second" in the description and claims of the present invention and the above drawings are used to distinguish similar objects, but not necessarily used to describe a specific sequence or sequence. It is to be understood that the data so used are interchangeable under appropriate ...

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Abstract

The invention belongs to the field of electrochemical sensors, and discloses a flexible enzyme-free glucose sensor electrode and a preparation method thereof. The flexible enzyme-free glucose sensor electrode comprises an Ecoflex flexible substrate, a plurality of Au nanowires are arranged on the Ecoflex flexible substrate, and Au nanoparticles are arranged at the end, away from the Ecoflex flexible substrate, of each Au nanowire. The method comprises the following steps: pasting a PET film on a glass plate to obtain a supporting layer, and coating Ecoflex glue on the surface of the supporting layer to form an Ecoflex flexible substrate; carrying out hydroxyl modification and amination treatment on the Ecoflex flexible substrate, soaking the Ecoflex flexible substrate in an Au nano seed solution for Au nano particle deposition to obtain an Ecoflex flexible substrate deposited with Au nano particles, and stripping the Ecoflex flexible substrate from the supporting layer; and placing the Ecoflex flexible substrate on which the Au nano-particles are deposited in an Au nano-wire growth solution, and carrying out Au nano-wire growth. The Au nanowires avoid warping and layering fracture of the electrode through excellent conductivity and ductility, the Au nanoparticles improve the sensing performance of the electrode through excellent catalytic performance, the preparation process is simple and safe, and batch preparation can be achieved.

Description

technical field [0001] The invention belongs to the field of electrochemical sensors, and relates to a flexible non-enzyme glucose sensor electrode and a preparation method thereof. Background technique [0002] Glucose is the main energy-supplying substance of organisms, and the glucose content in the blood has become an important indicator of human health. When the blood sugar level is too high, it will cause diabetes. According to the report of the International Diabetes Federation (IDF), about 463 million adults aged 20-79 suffer from diabetes in 2019, and it is estimated that by 2030, the number of diabetic patients will reach 578.4 million. Diabetes is difficult to cure, and if it is not controlled, it can lead to various complications such as stroke, blindness, kidney failure, and necrosis of lower limbs, which seriously threaten people's health. Therefore, frequent detection of glucose content in the blood is very important for the diagnosis and treatment of diabete...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/327G01N27/36
CPCG01N27/3278G01N27/36
Inventor 景蔚萱刘姝毛震李银河李友彬
Owner XI AN JIAOTONG UNIV
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