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An Electrically Controlled Observation System for Capturing Microfluidic Bubbles

An observation system and microfluidic technology, applied in the field of microfluidics, can solve problems such as low accuracy and poor stability, and achieve the effect of improving accuracy and stability and facilitating regulation

Active Publication Date: 2022-04-26
PEKING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] For this reason, the present invention provides an electric control observation system for capturing microfluidic bubbles, which can capture, observe and control the bubbles generated by microfluidics, and solve the problems of low accuracy and poor stability caused by the generation of bubbles in microfluidic experiments

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  • An Electrically Controlled Observation System for Capturing Microfluidic Bubbles
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  • An Electrically Controlled Observation System for Capturing Microfluidic Bubbles

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[0029] The implementation mode of the present invention is illustrated by specific specific examples below, and those who are familiar with this technology can easily understand other advantages and effects of the present invention from the contents disclosed in this description. Obviously, the described embodiments are a part of the present invention. , but not all examples. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0030] see figure 1 , figure 2 with image 3 , the embodiment of the present invention provides an electrical control observation system for capturing microfluidic bubbles, including a single photon counter 1, a high-speed camera 2, a picosecond pulse laser 3, a high-frequency voltage source 4, a trigger synchronization generator 5, and a spectroscopic prism 6 And microfluid observation assem...

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Abstract

An electrical control observation system for trapping microfluidic bubbles. Its single photon counter, high-speed camera, picosecond pulse laser and high-frequency voltage source are connected to a trigger synchronous generator; the microfluidic observation components include a cover layer, an introduction layer and The substrate; the surface of the cover layer is provided with a microchannel observation area; the introduction layer is between the cover layer and the substrate, the front end of the introduction layer is formed with a liquid inlet, the rear end of the introduction layer is formed with a liquid outlet, and the left end of the introduction layer is formed with a Picosecond pulse laser inlet, the right end of the introduction layer forms a picosecond pulse laser outlet; metal electrodes are deposited inside the groove of the substrate; On the prism, the single photon counter captures the light split by the beam-splitting prism for microscopic observation, and the high-speed camera captures the beam split by the beam-splitting prism for auxiliary observation. The invention is beneficial to control the air bubbles in the microfluid, and improves the accuracy and stability of the microfluid experiment.

Description

technical field [0001] The invention relates to the field of microfluidic technology, in particular to an electrical control observation system for trapping microfluidic bubbles. Background technique [0002] Microfluidics is the use of micropipes (tens to hundreds of microns in size) to process or manipulate tiny fluids (nanoliters to attoliters in volume), involving chemistry, fluid physics, microelectronics, new materials, biology and biomedical engineering emerging interdisciplinary disciplines. Because of the characteristics of miniaturization and integration, microfluidic devices are often called microfluidic chips, also known as lab-on-a-chip and micro-total analysis systems. One of the important features of microfluidics is the unique fluid properties in the micro-scale environment, such as laminar flow and droplets. With the help of these unique fluid phenomena, microfluidics can realize microfabrication and micromanipulation that are difficult to accomplish by co...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/01G01N21/51G01N21/84
CPCG01N21/01G01N21/51G01N21/84
Inventor 王振宇刘宗玺李伟张鑫钱文冰
Owner PEKING UNIV