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Creatinine test paper and preparation method thereof

A technology for testing test strips and creatinine, which is applied in the medical field and can solve problems such as inaccurate test results, large blood collection volume, and inaccurate test results

Active Publication Date: 2021-11-02
重庆云芯医联科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention aims at the problem of inaccurate test results caused by the interference of endogenous creatine in existing electrochemical creatinine test strips. The test of photochemical creatinine test strips requires a large amount of blood collection, long detection time, and inaccurate detection results. A creatinine test strip with fast detection time, less blood sampling volume, accurate detection results, and good matching with hospital detection results

Method used

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  • Creatinine test paper and preparation method thereof
  • Creatinine test paper and preparation method thereof
  • Creatinine test paper and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment one: as attached figure 1 , figure 2 Shown: a kind of creatinine test paper of the present embodiment, comprises PET substrate 7, electrode layer, ink layer 4, punching groove white glue layer 8, hydrophilic membrane layer 10 and cover sheet layer 11 successively from bottom to top; Electrode layer comprises Two sets of electrode areas and two reaction areas 3. The electrode areas are printed on PET sheets by screen printing with conductive silver paste, conductive carbon paste and insulating ink. Each set of electrode areas includes two reaction electrodes 2. A trigger electrode 1 full of blood, a recognition electrode 6 and a power-on electrode 12, each reaction zone 3 includes a reaction liquid, and the reaction liquid in the two reaction areas contains enzymes, wherein, The enzymes in the reaction liquid in one reaction zone 3 include 0.5U creatinase, 0.5U creatinase, 0.5U sarcosine oxidase and 0.3U peroxidase; The enzymes include 0.5U creatinase, 0.5U...

Embodiment 2

[0057] Such as figure 1 , figure 2 and Figure 4 As shown, on the basis of Embodiment 1, the end of the sampling port 5 is provided with a flexible connector 16 for externally connecting the blood collection needle, the flexible connector 16 is a silicone connector, and the end of the silicone connector is wrapped with a sterile coating The periphery of the connector; the longitudinal side of the electrode layer also has a sample reservation area, and the sample reservation area and the electrode area are separated by a punching white glue layer 8; a tear line is set between the sample reservation area and the electrode area 13. The tearing line 13 is a crimping line, and is formed after intermittent punching on the crimping line; the sample reserved area includes a sample reserved tube 14, which is a plastic tube, and one end of the plastic tube is connected to the sampling port 5 Connected, and form a reserved channel; the other end of the plastic tube is provided with a ...

Embodiment 3

[0060] In order to avoid the defect of the test paper being damp, a layer of desiccant paper is wrapped on the outer surface of the test paper, including the surrounding, upper surface and lower surface. Calcium chloride particles, of course, can also use other water-absorbing drying particles.

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Abstract

The invention belongs to the field of medical treatment and particularly provides creatinine test paper. The creatinine test paper sequentially comprises a PET substrate, an electrode layer, an ink layer, a notching white glue layer, a hydrophilic film layer and a cover plate layer from bottom to top, wherein the electrode layer comprises two groups of electrode areas and two reaction areas, each group of electrode areas comprises two reaction electrodes, a full blood trigger electrode, an identification electrode and a startup electrode, and each reaction area comprises reaction liquid medicine; the ink layer covers the electrode layer, a sampling port is reserved in the end part of one end, opposite to the startup electrode, of the ink layer, the sampling port is respectively communicated with the two groups of reaction areas, and the ink layer is exposed out of the electrode area and the reaction areas; the notching white glue layer covers the electrode layer and is filled between the sampling ports to isolate the two reaction areas; the notching white glue layer is covered with the hydrophilic film layer, and an exhaust hole is reserved in the position, above the sampling opening, of the hydrophilic film layer; and the cover sheet layer is positioned above the hydrophilic film layer, and the exhaust holes are exposed out of the cover sheet layer. Compared with the prior art, the result test is more accurate; the detection speed is high, whole blood can be directly used for detection without blood filtration, and the blood collection amount is small.

Description

technical field [0001] The invention belongs to the medical field, and in particular relates to a creatinine test paper and a preparation method thereof. Background technique [0002] Creatinine (Cr) is a nitrogenous compound with low molecular weight in the human body, which is a product of muscle metabolism in the human body. Serum creatinine comes from both exogenous and endogenous sources. Exogenous creatinine is the product of meat food metabolism in the body; endogenous creatinine is the product of muscle tissue metabolism in the body. In the case of stable exogenous creatinine intake and constant body production, the serum creatinine concentration mainly depends on the filtration function of the glomerulus. When the glomerular filtration rate drops to 1 / 3 of the normal person, the serum creatinine rises significantly. Therefore, when the serum creatinine is significantly higher than the normal value, it often indicates that the renal function has been seriously damag...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/327G01N21/78
CPCG01N27/3272G01N21/78
Inventor 郭劲宏
Owner 重庆云芯医联科技有限公司
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