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Manufacturing method of intraosseous blood vessel anatomy display specimen and specimen

A production method and blood vessel technology, applied in the field of biological specimens to achieve the effect of reducing postoperative recurrence

Active Publication Date: 2021-11-05
青岛山大齐鲁医院(山东大学齐鲁医院(青岛))
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0012] However, in the tibiofemoral LC channel in children that we found in this study, the tunnel passes from the joint cavity into the intercondyle, and the small blood vessels of the middle knee vessel contained in it enter the epiphysis of the tibia or femur, and run longitudinally through the entire epiphysis and epiphysis. Plate, and into the metaphysis, became a penetrating vessel not seen in previous reports

Method used

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  • Manufacturing method of intraosseous blood vessel anatomy display specimen and specimen
  • Manufacturing method of intraosseous blood vessel anatomy display specimen and specimen
  • Manufacturing method of intraosseous blood vessel anatomy display specimen and specimen

Examples

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Embodiment 1

[0094] This embodiment provides a method for making intraosseous blood vessel anatomy display specimens. The cases, image data and human specimens in this embodiment are all from Qilu Hospital of Shandong University and Qingdao Campus of Qilu Hospital of Shandong University.

[0095] Tumor knee anatomy specimens:

[0096] A total of 22 human complete tumor knee joint specimens were collected from May 2017 to March 2020. The sources of materials included fresh specimens after amputation (12 cases) and fresh specimens after tumor resection (10 cases).

[0097] Inclusion criteria: 1. Distal femoral and tibial invasive tumors resected with clear pathological diagnosis; 2. Primary malignant bone tumors of the tibia and femur, with tumor segment resection or amputation and clear pathological diagnosis; 3. Knee joint cavity Intracondylar primary invasive tumors, resection of tumor segments, postoperative pathologically clear; 4. Those who meet the inclusion criteria 1.2.3, the preop...

Embodiment 2

[0115] This example provides a method for making an adult intraosseous LC pathway display specimen. In this example, the cases, image data, and human specimens are all from Qilu Hospital of Shandong University and Qingdao Campus of Qilu Hospital of Shandong University.

[0116] From May 2017 to March 2020, a total of 200 cases (200 knees) of the knee joint CT1mm thin-slice plain scan + 3D reconstruction were used in the image center database, and 100 cases (100 knees) of the knee joint were MRI plain scan or enhanced images. Including knee joint trauma, knee degenerative disease, meniscus injury, anterior cruciate ligament, posterior cruciate ligament, lateral collateral ligament injury, primary invasive tumor of the knee joint, knee joint malignant tumor patients and general physical examination patients. CT data are mainly used to demonstrate the ubiquity and location distribution of the tibial intercondylar foramen and femoral intercondylar foramen, and MRI data are mainly u...

Embodiment 3

[0127] This example provides a method for making a display specimen of intraosseous LC pathway in children. The cases, imaging data and human specimens in this example are all from Qilu Hospital of Shandong University and Qingdao Campus of Qilu Hospital of Shandong University.

[0128] From May 2017 to March 2020, there were 50 cases (50 knees) of children in the imaging center database with CT 1mm thin-slice plain scan + 3D reconstruction, and 30 cases (30 knees) with knee MRI 1mm thin-slice plain scan or enhanced images . Including patients with knee joint injury, discoid meniscus, osteomyelitis, lower extremity osteochondroma, knee joint malignant tumor and general physical examination. CT data are mainly used to demonstrate the prevalence of tibial intercondylar foramen and femoral intercondylar foramen in children, and the channel properties of the LC pathway in the epiphysis and metaphysis, and MRI data are mainly used to demonstrate the content of the LC pathway and wa...

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Abstract

The invention discloses a manufacturing method of an intraosseous blood vessel anatomy display specimen and the specimen. The method comprises the steps: obtaining a fresh femur or tibia specimen; removing bone cortex, and soaking and fixing in formalin; using an EDTA decalcifying agent for soaking and decalcifying; using CT thin layer scanning to find a femoral intercondylar foramen or a tibia intercondylar eminence foramen; dissecting from the femoral intercondylar foramen or the tibia intercondylar eminence foramen, and exposing blood vessels and the intraosseous blood vessel ducts for accommodating the blood vessels; putting the dissected skeleton specimen into a container box, adding resin to submerge the skeleton specimen, and enabling the resin to gradually enter the skeleton specimen; putting the container box into a constant-temperature box, removing the container box after the resin is hardened, and taking out the specimen; and cutting off excess resin, grinding and polishing and completing manufacturing. By using the manufacturing method disclosed by the invention, intraosseous blood vessel ducts and intraosseous blood vessels can be completely exposed, and existence and distribution of the intraosseous blood vessels in bones can be intuitively displayed; and if the specimen is a child skeleton specimen, the situation that the intraosseous blood vessels pass through the epiphyseal plate can be revealed.

Description

technical field [0001] The invention relates to the technical field of biological specimens, in particular to a method for preparing a specimen for anatomical display of intraosseous blood vessels and the specimen. Background technique [0002] Because there are many classic anatomical structures in and around the knee joint, and it is a predilection site for many common sports injuries, degeneration, tumors, and traumas, it has been a hot topic of research by orthopedics and anatomy scholars for nearly a century. There are classic anatomical structures such as tibial plateau, femoral condyle and intercondylar fossa, anterior and posterior cruciate ligaments, medial and lateral menisci, etc., and its macroscopic structure and related clinical significance have been more maturely studied. In recent years, the knee joint has been newly named Anatomical structures are rare. [0003] There is also a relatively mature theoretical system about the source of blood supply and vascu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N1/00G09B23/30G09B23/28
CPCA01N1/00G09B23/306G09B23/28
Inventor 程坤李建民李玉椿李秋尧侯海青金利新高晓斐冯琨杨志成杨强邵显昊蒙思瑜
Owner 青岛山大齐鲁医院(山东大学齐鲁医院(青岛))
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