Radiotherapy target region establishment and correction method based on dose distribution preview system

Abstract

The embodiment of the invention discloses a radiotherapy target region establishment and correction method based on a dose distribution preview system. The method comprises the following steps: reading CT image data, PTV contours and OARs contours; processing the CT image data and the PTV contour to obtain a processing result, wherein the processing result comprises a 3D dose distribution diagram, a DVH diagram, a concerned dose index and an HI / CI index; and on the basis of a processing result, carrying out engraving type correction on the PTV contour, so that the corrected PTV contour achieves a balance between ensuring the focus stress and reducing the risk of the crisis organ. The dose distribution preview system is designed based on deep learning, the target region modification and plan making process is simplified through the system, the rationality of radiotherapy target region establishment and the radiotherapy plan quality are improved, the treatment delay time of tumor patients is shortened, the burden of workers is reduced, and meanwhile the radiotherapy curative effect of the patients is improved.

Description

technical field [0001] The invention relates to the field of computer technology, in particular to a method for establishing and correcting a radiotherapy target area based on a dose distribution preview system. Background technique [0002] With the development of radiobiology and computer technology, radiation therapy (Radiation Therapy, RT) is increasingly playing an irreplaceable role in tumor treatment. The rational formulation of radiotherapy plan (RT Plan) is the basis to ensure the accuracy and good curative effect of radiotherapy, and in this process, the determination of radiotherapy target volume is an important prerequisite for plan formulation. The target volume is usually divided into three levels: GTV (Gross Tumor Volume, rough tumor target volume), CTV (Clinical Target Volume, clinical target volume) and PTV (Planning Target Volume, planning target volume). Among them, PTV is the key reference object for field layout, dose calculation, and plan evaluation. I...

AI Technical Summary

Problems solved by technology

[0010] (6) For radiotherapy plans that have been optimized repeatedly but still cannot meet the clinical requirements (high enough target dose, good uniformity and conformity, and low risk of organ-at-risk), the oncologist should reasonably revise the PTV contour and give feedback to the patient. Physicist reworks radiotherapy plan

[0014] (1) In the process of modifying the radiotherapy target area, the oncologist lacks the overall dose distribution prediction, dose index (or DVH map), HI\CI and other estimation methods corresponding to the current PTV, making it difficult to establish the PTV area in a guaranteed manner. Find a balance between prescribing therapeutic doses (necessary for the lesion and its surrounding area) and reducing risk to organs at risk (normal tissues and organs)

On the one hand, in order to ensure the dose of the lesion, while considering the elimination of the uncertainty of the irradiation dose caused by factors such as organ movement, shape change, setup error, and image error, it may cause the PTV boundary to expand excessively; on the other hand, for In cases where the original lesion is large in size, close to or overlapping with the organ at risk or SIB (simultaneous boost), due to the consideration of minimizing the dose of the organ at risk, the expansion of the PTV boundary may be insufficient

[0015] (2) Due to differences in clinical experience and professional level, different clinical workers have different speeds and effects of corrections in the PTV area, and accordingly, it will affect the cycle and quality of plan formulation

[0016] (3) For radiotherapy plans that have not yet obtained the ideal dose distribution, dose index (or DVH map), and HI / CI indicators after repeated optimization but still do not meet clinical requirements, it is difficult for physicists to determine whether the reason comes from unreasonable PTV or From mistakes in planning design process

Therefore, for some special (lesion volume or location) cases, the process of PTV revision and plan re-enactment will consume a lot of time and energy, the delay of patient treatment time and the change of lesion volume during this period will reduce the accuracy of radiotherapy, resulting in the actual lesion Insufficient dose or damage to normal tissues and organs, etc.

Images