Stasis-removing and turbidity-descending prescription for treating gout

A technology for removing blood stasis and lowering turbidity, which is applied in the direction of medical formulas, medical preparations containing active ingredients, plant raw materials, etc., and can solve problems such as inability to effectively avoid gout recurrence, high incidence of adverse reactions, and acute recurrence of gout symptoms

Active Publication Date: 2021-11-30
陕西省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although Western medicine can effectively reduce uric acid levels, control acute attacks, and relieve clinical symptoms in terms of treatment, there are still some deficiencies: ①The timing, target and possible adverse effects of uric acid lowering are still controversial; ②In clinical practice, the initial application of urate-lowering drugs is likely to lead to acute recurrence of gout symptoms, and lowering urate can not effectively prevent the recurrence of gout. Some studies have shown that febuxostat and allopurinol are effective in the treatment of urate-lowering for one year. , 53% of patients had their SUA controlled at ≤6mg·dL -1 , but the recurrence rate of gout is still 63%
③The incidence of adverse reactions of long-term medication is high

Method used

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  • Stasis-removing and turbidity-descending prescription for treating gout
  • Stasis-removing and turbidity-descending prescription for treating gout
  • Stasis-removing and turbidity-descending prescription for treating gout

Examples

Experimental program
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Effect test

Embodiment 1

[0010] A prescription for dispelling blood stasis and reducing turbidity for treating gout, which is prepared from the following components: 15g of fried atractylodes rhizome; 10g of Achyranthes bidentata; 9g of Cortex Phellodendri; 15g of fried coix seed; 9g of angelica; 10g of rehmannia root; Poria 12g; Plantago 15g; Zhilicorice 6g; Salvia miltiorrhiza 12g; Rhubarb 3g.

Embodiment 2

[0012] A prescription for dispelling blood stasis and reducing turbidity for treating gout, which is prepared from the following components: 20g of fried atractylodes rhizome; 15g of Achyranthes bidentata; 12g of Phellodendron cortex; 30g of fried coix seed; 12g of angelica; Poria cocos 15g; plantago seed 30g; roasted licorice 9g; salvia miltiorrhiza 15g; rhubarb 6g.

Embodiment 3

[0014] A prescription for dispelling blood stasis and reducing turbidity for treating gout, which is prepared from the following components: 17.5 g of fried atractylodes rhizome; 12.5 g of Chuan Achyranthes bidentata; 10.5 g of Cortex Phellodendri; 22.5 g of fried coix seed; 10.5 g of angelica; 12.5 g of rehmannia; Chuanxiong 11g; Atractylodes macrocephala 22.5g; Poria cocos 13.5g; Plantago 22.5g; Zhilicorice 7.5g; Salvia miltiorrhiza 13.5g; Rhubarb 4.5g.

[0015] clinical information:

[0016] Methods: A total of 60 patients who met the diagnostic criteria of gouty arthritis in the remission stage were selected, and the TCM diagnosis and syndrome type belonged to the type of spleen deficiency and dampness, blood stasis blocking collaterals, and were randomly divided into treatment groups (Treatment with Quyu Jiangzhuo Decoction, 30 cases) Compared with the control group (benzbromarone treatment, 30 cases), blood uric acid levels, symptom and syndrome scores, blood lipids, blo...

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Abstract

The invention relates to the field of traditional Chinese medicine preparations, and particularly relates to a stasis-removing turbidity-descending prescription for treating gout. The prescription is prepared from the following raw materials: fried rhizoma atractylodis, radix cyathulae, cortex phellodendri, fried semen coicis, radix angelicae sinensis, radix rehmanniae recen, rhizoma chuanxiong, fried rhizoma atractylodis macrocephalae, poria cocos, semen plantaginis, radix glycyrrhizae preparata, radix salviae miltiorrhizae and radix et rhizoma rhei. The stasis-removing and turbidity-descending prescription has the effects of strengthening spleen and middle warmer, dispersing blood stasis and promoting diuresis, consolidating constitution and removing blood stasis by synergistic effect of the raw materials, can effectively relieve symptoms of patients, and effectively reduce uric acid and blood fat with few adverse reactions, less gout proneness and satisfactory clinical effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a prescription for removing blood stasis and reducing turbidity for treating gout. Background technique [0002] Gout is a clinical syndrome characterized by abnormal purine metabolism in the body, increased serum uric acid concentration, and chronic deposition of monosodium urate crystals in joint capsules, synovial bursa, cartilage, bone and other tissues due to metabolic and genetic factors, causing inflammatory reactions and lesions. , which is directly related to hyperuricemia caused by decreased uric acid excretion and / or purine metabolism disorder, is the second largest metabolic disease in my country. With the improvement of socio-economic level and people's living standards, the prevalence of gout is increasing year by year and the age of onset is getting younger and younger. If the disease is not treated properly and relapses, it can lead to comp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P19/06A61P19/02A61P3/06
CPCA61K36/284A61K36/21A61K36/756A61K36/8994A61K36/232A61K36/804A61K36/236A61K36/076A61K36/68A61K36/484A61K36/537A61K36/708A61P19/06A61P19/02A61P3/06A61K2300/00
Inventor 肖洋柯婷杭程祁海燕王高雷王露露师韩菲董丹丹成路平刘厚利钟艺鸣吴宇祥高向宏
Owner 陕西省中医医院
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