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Repair factor-loaded suture line production device

A technology for repairing factors and production devices, which is applied in the fields of filament generation, final product manufacturing, and textile material carrier processing, which can solve problems such as excessive drug intake side effects, secondary damage to skin tissue, and poor therapeutic effects, and achieve improved release The effect of speed, increase of contact area, and relief of pain symptoms

Active Publication Date: 2021-11-30
NORTHWESTERN POLYTECHNICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, some clinical drugs need to be injected into large doses to play a role, which not only has the risk of excessive drug intake and the disadvantages of strong side effects, but also reaches the lesion through blood circulation relatively slowly, resulting in poor therapeutic effect. Topical administration is an effective way to enhance drug action and therapeutic efficacy
[0003] The existing sutures are usually loaded with repair factors or nanoparticles directly through the hydrolyzable sutures to improve the speed and effect of wound healing. However, after the production of the existing sutures, the surface of some sutures is relatively rough, which leads to sutures. During the suturing process, the suture produces secondary damage to the skin tissue at the suture, and the release rate of repair factors or nanoparticles on the existing suture is also slow, and the wound healing effect and speed are often poor

Method used

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  • Repair factor-loaded suture line production device
  • Repair factor-loaded suture line production device
  • Repair factor-loaded suture line production device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] see figure 1 and figure 2 , a suture production device loaded with repairing factors, including a base plate 1, a spinning device 2 is fixed on the top of the base plate 1, a material outlet is opened on the front side of the spinning device 2, two material inlets are opened on the right side, and a built-in 5kV The power supply, the two feed inlets of the spinning device 2 are respectively connected to the discharge end of the spinning solution injector 3 and the repair factor injector 4, the repair factor injector 4 internal solution contains repair factors or nanoparticles, and the repair factors or nanoparticles can be Restoration drugs, anti-inflammatory drugs, repair proteins and other substances, the bottoms of the spinning solution syringe 3 and the repair factor syringe 4 are fixed to the top of the base plate 1, and the driving pistons inside the spinning solution syringe 3 and the repair factor syringe 4 are respectively connected to the push pump-5 It is f...

Embodiment 2

[0038] see figure 1 and figure 2 , on the basis of Example 1,

[0039] In this embodiment, in order to make the suture thread in the shape of a core shell and the shell layer distributed in a discontinuous shape, the spinning solution inside the spinning solution injector 3 is a degradable fiber with elastic stretching effect, and the internal mixing solution of the repairing factor injector 4 also contains For polyglycolic acid, propulsion pump one 5 is a continuous propulsion pump, and propulsion pump two 6 is an intermittent propulsion pump.

[0040] In this embodiment, since the solution in the repair factor injector 4 is a repair factor or a mixture of nanoparticles and polyglycolic acid, the suture spun by the spinning device 2 is composed of the degradable fiber core layer of the spinning solution injector 3 and the repair factor. The degradable shell of the syringe 4 is composed of polyglycolic acid as the carrier of the repair factor or nanoparticles, which can imp...

Embodiment 3

[0042] see Figure 3-4 , on the basis of Example 2,

[0043] A suture production device carrying a repair factor, the part between the outlet of the spinning device 2 and the winding wheel 71 is provided with a dipping mechanism 8, the dipping mechanism 8 includes a dipping tank 81, and the input end of the dipping tank 81 is provided with a conductive The front and rear sides of the wire groove 82 and the inside of the dip dyeing groove 81 are all fixedly connected with an air bag 83 , and the inside of the dip dyeing groove 81 and one end close to the conductive wire groove 82 is rotatably connected with a guide wheel 84 .

[0044] A discharge port 85 is provided at the output end of the dipping tank 81 and corresponding to the conducting wire slot 82 , and a limiting wheel 86 is provided inside the dipping tank 81 and near the discharge port 85 . The suture is input from the conduction line groove 82 to the inside of the dipping tank 81, and the dipping tank 81 stores the ...

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Abstract

The invention discloses a repair factor-loaded suture line production device. The repair factor-loaded suture line production device comprises a bottom plate, wherein a spinning device is fixed to the top of the bottom plate; a discharging port is formed in the front side of the spinning device; two feeding ports are formed in the right side of the spinning device; a 5kV power source is arranged in the spinning device; the two feeding ports of the spinning device are connected with the discharging end of a spinning solution injector and the discharging end of a repair factor injector respectively; a solution in the repair factor injector contains repair factors or nano particles; and the bottom of the spinning solution injector and the bottom of the repair factor injector are both fixed to the top of the bottom plate. The repair factor-loaded suture line production device provided by the invention relates to the technical field of suture line production. According to the repair factor-loaded suture line production device, continuous input of a spinning solution and intermittent input of repair factors are achieved, so that a surface shell layer of a suture line spun by a spinning device is in an intermittent state, the contact area between an upper shell layer part of the suture line and body tissues can be increased, and then the release speed of the repair factors or the nano particles is improved.

Description

technical field [0001] The invention relates to the technical field of suture production, in particular to a suture production device carrying a repair factor. Background technique [0002] Sutures are widely used in clinical operations and play an important role in suturing wounds and connecting damaged tissues. With the development of technology, the materials used for sutures have also been continuously improved, and their functions have been further enhanced. Generally speaking, drugs must maintain an effective concentration for a long time at the lesion site in the patient's body to exert a good effect. At present, some clinical drugs need to be injected into large doses to play a role, which not only has the risk of excessive drug intake and the disadvantages of strong side effects, but also reaches the lesion through blood circulation relatively slowly, resulting in poor therapeutic effect. Topical administration is an effective way to enhance drug action and therap...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D01D1/06D01D11/00D06B3/04D06B15/06D06B23/04A61L17/00
CPCD01D1/065D01D11/00D06B3/04D06B15/06D06B23/04A61L17/00Y02P70/62
Inventor 叶雅静尹大川许艺凡侯亚波
Owner NORTHWESTERN POLYTECHNICAL UNIV
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