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A repair factor-loaded suture production device

A technology for repairing factors and production devices, which is applied in the direction of filament generation, final product manufacturing, and textile material carrier processing, etc. It can solve problems such as side effects of excessive drug intake, secondary damage to skin tissue, and poor therapeutic effects, so as to prevent mutual Effects of friction, increased release speed, and increased contact area

Active Publication Date: 2022-07-05
NORTHWESTERN POLYTECHNICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, some clinical drugs need to be injected into large doses to play a role, which not only has the risk of excessive drug intake and the disadvantages of strong side effects, but also reaches the lesion through blood circulation relatively slowly, resulting in poor therapeutic effect. Topical administration is an effective way to enhance drug action and therapeutic efficacy
[0003] The existing sutures are usually loaded with repair factors or nanoparticles directly through the hydrolyzable sutures to improve the speed and effect of wound healing. However, after the production of the existing sutures, the surface of some sutures is relatively rough, which leads to sutures. During the suturing process, the suture produces secondary damage to the skin tissue at the suture, and the release rate of repair factors or nanoparticles on the existing suture is also slow, and the wound healing effect and speed are often poor

Method used

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  • A repair factor-loaded suture production device
  • A repair factor-loaded suture production device
  • A repair factor-loaded suture production device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] see figure 1 and figure 2 , a repair factor-carrying suture production device, comprising a bottom plate 1, a spinning device 2 is fixed on the top of the bottom plate 1, a discharge port is provided on the front side of the spinning device 2, and two feed ports are provided on the right side, with a built-in 5kV The power supply, the two feed ports of the spinning device 2 are respectively connected with the spinning solution injector 3 and the discharge end of the repair factor injector 4. The solution inside the repair factor injector 4 contains repair factors or nanoparticles, and the repair factors or nanoparticles can be Repair drugs, anti-inflammatory drugs, repair proteins and other substances, the bottom of the spinning solution syringe 3 and the repair factor syringe 4 are fixed with the top of the bottom plate 1, and the driving pistons inside the spinning solution syringe 3 and the repair factor syringe 4 are respectively connected with the propelling pump ...

Embodiment 2

[0038] see figure 1 and figure 2 , on the basis of Example 1,

[0039] In this embodiment, in order to make the sutures have a core-shell shape and the shell layers are distributed intermittently, the spinning solution inside the spinning solution syringe 3 is a degradable fiber with elastic stretching effect, and the mixed solution inside the repair factor syringe 4 also contains: For polyglycolic acid, the propelling pump 1 5 is a continuous propelling pump, and the propelling pump 2 6 is an intermittent propelling pump.

[0040] In this embodiment, since the solution in the repair factor injector 4 is a mixture of repair factor or nanoparticles and polyglycolic acid, the suture spun by the spinning device 2 is composed of the degradable fiber core layer and the repair factor of the spinning solution injector 3 The degradable shell layer of the syringe 4 is constituted, and the polyglycolic acid as the carrier of the repair factor or the nanoparticle can improve the stabi...

Embodiment 3

[0042] see Figure 3-4 , on the basis of Example 2,

[0043] A repair factor-carrying suture production device, the part between the discharge port of the spinning device 2 and the reel 71 is provided with a dip-dyeing mechanism 8, the dip-dyeing mechanism 8 includes a dip-dye tank 81, and the input end of the dip-dye tank 81 is provided with a conduction In the wire groove 82 , air bags 83 are fixedly connected to the front and rear sides of the inside of the dyeing groove 81 , and a wire wheel 84 is rotatably connected to the end of the dyeing groove 81 close to the conducting wire groove 82 .

[0044] A discharge port 85 is provided at the output end of the dyeing tank 81 and at a position corresponding to the conductive wire groove 82 , and a limiting wheel 86 is provided inside the dyeing tank 81 and near the discharge port 85 . The suture is input from the conducting wire groove 82 to the interior of the impregnation tank 81, and the impregnation tank 81 stores the impr...

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Abstract

The invention discloses a repair factor-carrying suture production device, which comprises a bottom plate, a spinning device is fixed on the top of the bottom plate, a discharge port is provided on the front side of the spinning device, two intake ports are provided on the right side, and a built-in 5kV power supply is provided. , the two feeding ports of the spinning device are respectively connected with the output ends of the spinning solution injector and the repair factor injector, the solution inside the repair factor injector contains repair factor or nanoparticles, and the bottoms of both the spinning solution injector and the repair factor injector are connected to the bottom plate Top fixing, the present invention relates to the technical field of suture production. The repair factor-loaded suture production device achieves the continuous input of the spinning solution and the intermittent input of the repair factor, so that the surface shell of the suture spun by the spinning device is in an intermittent state, which can increase the shell layer on the suture. Part of the contact area with body tissue, thereby increasing the release rate of repair factors or nanoparticles.

Description

technical field [0001] The invention relates to the technical field of suture thread production, in particular to a repair factor-loaded suture thread production device. Background technique [0002] Sutures are widely used in clinical operations and play an important role in suturing wounds and connecting damaged tissues. With the development of technology, the materials used for sutures are also constantly improving and their functions are further enhanced. Generally speaking, the effective concentration of the drug must be maintained for a long time in the lesion site of the patient in order to exert a good effect. At present, some clinical drugs need to be injected in large doses intravenously to play their role, which not only has the disadvantage of excessive drug intake and strong side effects, but also reaches the lesions relatively slowly through blood circulation, resulting in poor therapeutic effect. Topical administration is an effective method to enhance drug ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): D01D1/06D01D11/00D06B3/04D06B15/06D06B23/04A61L17/00
CPCD01D1/065D01D11/00D06B3/04D06B15/06D06B23/04A61L17/00Y02P70/62
Inventor 叶雅静尹大川许艺凡侯亚波
Owner NORTHWESTERN POLYTECHNICAL UNIV
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