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Processing method of processed rhizoma typhonii

A technology for preparing white aconite and white aconite, which is applied in the field of traditional Chinese medicine preparations, can solve the problems of loss of water-soluble active ingredients, unsatisfactory content of extracts of prepared white aconite, and unsatisfactory content standards of extracts, etc., so as to prevent water-soluble active ingredients. drain effect

Pending Publication Date: 2021-12-07
BEIJING KANGRENTANG PHARMA
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  • Summary
  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0005] Long-term water immersion and boiling in the above-mentioned processing methods recorded in the Pharmacopoeia can certainly remove toxicity, but therefore also cause the loss of water-soluble active ingredients (Ye Dingjiang, "Chinese Medicine Processing Dictionary", Shanghai Science and Technology Press, 2005, the first Edition: 222-224)
This just causes the extract content of Radix Aconiti Radix L. obtained after processing to not meet the standard of Chinese Pharmacopoeia: "Chinese Pharmacopoeia" 2015 edition requires for Radix Radix Radix Radix Radix Radix Lv. 2201) measured by hot dip method, use dilute ethanol as solvent, not less than 15.0%"
For example: Cheng Liping pointed out in an article titled "Determination and Comparison of Extract Content of Different Processed Products of Radix Aconiti Radix" published at the Chinese Medicine Processing Branch of the Chinese Association of Traditional Chinese Medicine (2008) that the processed products obtained according to the processing method in the Pharmacopoeia The ethanol extract content of the decoction pieces is only about 0.6%, which does not meet the extract content standard in the Pharmacopoeia
In the article titled "Research on Yubai Additional Pressure Processing Technology" published in Chinese Medicinal Materials (2010), Zhao Suxia and others pointed out that the ethanol extract content of the processed decoction pieces prepared according to the processing method in the Pharmacopoeia is only 1.4-5.1%. , does not meet the standard of extract content in Pharmacopoeia
[0006] And the norm of local processing also can't produce the decoction piece that meets pharmacopoeia requirement (extract is unqualified), and existing other processing method is research processing mechanism mostly, does not see the report of the processing method that improves extract content

Method used

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Embodiment 1

[0043] The present embodiment provides a kind of processing method of Radix Aconitie decocting pieces, specifically comprises the following steps:

[0044] Put the Radix Aconitie through a 2cm sieve, weigh 20kg of the Radix Abdomonas on the sieve, put it in the washing liquid tank, then add 20kg of drinking water to soak for 30 hours until the aqueous solution becomes viscous (stir once every 24 hours during the soaking process, and do not change the water during the whole process); then Pull out the Radix Aconiti, change 40kg of 6wt% alum water and soak for 7 days until there is no dry heart in the Radix Aconiti and there is a slightly numb tongue feeling in the mouth, take it out, then put the Radix Aconite taken out with 2.5kg of ginger slices and 0.1kg of alum powder layer by layer Stack (i.e. set up layer by layer according to the order of white aconite, ginger slices, and alum powder) into the steaming drawer, put it in a traditional Chinese medicine cooking interlayer po...

Embodiment 2

[0046] The present embodiment provides a kind of processing method of Aconite Radix, specifically comprises the following steps:

[0047] Put the Radix Aconitie through a 5cm sieve, weigh 20kg of the Radix Aconitie on the sieve, add 10kg of drinking water to soak for 48 hours until the aqueous solution becomes viscous (stir once every 24 hours, do not change the water during the whole process), remove the Radix Aconiti, Change 20kg of 12wt% alum water and soak for 8 days until there is no dry heart in the Aconite, and there is a numb tongue feeling slightly in the mouth, take it out, and add 2.5kg of ginger slices, and 0.1kg of alum powder. The sequence of powder is set layer by layer) into the steaming drawer, placed in the traditional Chinese medicine cooking interlayer pot, steamed for 27 hours until there is no white heart in the white aconite, and the color deepens, stop heating, take it out, remove the ginger slices, and put it in a high-temperature heat pump at 10°C for ...

Embodiment 3

[0049]The present embodiment provides a kind of processing method of Radix Aconitie decocting pieces, specifically comprises the following steps:

[0050] Pass the Radix Aconitie through a 1cm sieve, weigh 20kg of the Radix Abdomonas on the sieve, add 60kg of drinking water to the washing liquid tank and soak for 24 hours until the aqueous solution becomes viscous (do not change the water during the whole process), remove the Radix Aconitie, and replace it with 4wt% Soak 60kg of alum water for 4 days until there is no dry heart in the aconite, and there is a slight numbness in the mouth, take it out, add 2.5kg of ginger slices, and add 0.1kg of alum powder layer by layer (that is, follow the order of aconite, ginger slices, and alum powder (set layer by layer) into the steaming drawer, put it in a traditional Chinese medicine steaming interlayer pot, steam for 12 hours until there is no white heart in the white aconite, and the color deepens, stop heating, take it out, remove t...

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Abstract

The invention provides a processing method of processed rhizoma typhonii. The processing method comprises the following steps that rhizoma typhonii soaked in alum water, ginger slices and alum powder are stacked, steaming is achieved, taking out is achieved, the ginger slices are removed, and moistening is achieved to obtain processed rhizoma typhonii decoction pieces. According to the processing method of the processed rhizoma typhonii, the rhizoma typhonii soaked in the alum water, the ginger slices and the alum powder are stacked layer by layer and steamed until no white core exists in the rhizoma typhonii, the extract content of the processed rhizoma typhonii can be remarkably increased, the requirement that the extract content is not lower than 15% in the Chinese pharmacopoeia is met, and the toxicity of the rhizoma typhonii can be fully removed.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a processing method for preparing Radix Aconiti. Background technique [0002] Aconite is the dried tuber of Typhonium giganteum Engl., a plant of the family Araceae. It is warm in nature and pungent in taste. It can be used for apoplexy with phlegm congestion, slanted mouth and eyes, astringent speech, phlegm reversal, headache, hemiplegia headache, sore throat and sore throat, tetanus syndrome, external treatment of scrofula with sputum nucleus, snake bites and other syndromes. [0003] The raw and fresh products of Aconite Radix are poisonous, have a strong spicy tongue-tingling sensation, and have strong irritating effects on the mucous membranes of the mouth, throat, eyes, and stomach (Zhu Tao, Wu Hao, Zhang Lin, Chen Lei, Chen Lin, Yu Preliminary study on the irritant and toxic components of Radix Cortex Radix, Journal of Nanjing Universit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61K125/00A61K36/9068A61K33/06
CPCA61K36/888A61K36/9068A61K33/06A61K2236/10A61K2300/00
Inventor 付静张志强周永康张伟娜闫晓鑫
Owner BEIJING KANGRENTANG PHARMA