Pharmaceutical composition for treating femoral head necrosis and application thereof

A femoral head necrosis and composition technology, which is applied in the field of pharmaceutical compositions, can solve the problems of unsatisfactory curative effect and long treatment cycle, and achieve the effect of benefiting new bone cells, increasing blood supply, and promoting new bone cells

Pending Publication Date: 2021-12-31
黄琛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine mainly treats from the aspects of dredging blood collaterals, promoting blood circulation and regulating qi, promoting new life and relieving pain, but the curative effect is not satisfactory and the treatment cycle is long

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The pharmaceutical composition for treating femoral head necrosis is mainly made of the following components in weight ratio: royal jelly capsule 1000mg, diclofenac sodium 100mg, vitamin B1 20mg, omeprazole 20mg.

[0021] The pharmaceutical composition is administered orally, taken 15 minutes after meals, twice a day, 10 days as a course of treatment.

Embodiment 2

[0023] The pharmaceutical composition for treating femoral head necrosis is mainly made of the following components in weight ratio: royal jelly 1200mg, diclofenac sodium 80mg, vitamin B1 20mg, omeprazole 20mg.

Embodiment 3

[0025] The pharmaceutical composition for treating femoral head necrosis is mainly made of the following components in weight ratio: royal jelly capsule 900mg, diclofenac sodium 90mg, vitamin B1 15mg, omeprazole 15mg.

[0026] In order to show the therapeutic effect of the present invention on femoral head necrosis, the inventor has carried out clinical observation and treatment to 600 cases, 300 people in the test group, 300 people in the control group, the test group uses the medicine obtained in embodiment 1, and the control group uses other treatments for femoral head Drugs for necrosis. Among them, there were 520 males and 106 females, aged 18-74 years. Among them, there are 216 patients in the first grade, 320 patients in the second grade, and 90 patients in the third grade.

[0027] Diagnosis basis: early limp, hip and knee soreness, stiffness, pain during activities, and improvement after rest; limited hip movement, the earliest being limited rotation, later involving...

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Abstract

The invention discloses a pharmaceutical composition for treating femoral head necrosis and application of the pharmaceutical composition in preparation of products for preventing and / or treating various types of femoral head necrosis. The pharmaceutical composition is prepared from the following raw materials royal jelly, diclofenac sodium, vitamin B1 and omeprazole, preferably, the pharmaceutical composition is prepared from the following raw materials in parts by weight: 30-70 parts of royal jelly, 3-7 parts of diclofenac sodium, 1-3 parts of vitamin B1 and 1-3 parts of omeprazole. The pharmaceutical composition can be used for treating various types of femoral head necrosis, especially femoral head necrosis needing surgical treatment, and is less in patient pain and good in compliance. The effective rate of the pharmaceutical composition for treating femoral head necrosis can reach 90.0%, and the cure rate can reach 81.7%.

Description

technical field [0001] The invention belongs to the field of pharmaceutical compositions, in particular to a pharmaceutical composition for treating necrosis of the femoral head and its application in preparing products for preventing and / or treating various types of necrosis of the femoral head. Background technique [0002] Femoral head necrosis is a disease in which the blood supply to the femoral head is interrupted or damaged, resulting in the death and subsequent repair of bone cells and bone marrow components, which in turn leads to structural changes in the femoral head, collapse of the femoral head, and joint dysfunction. Osteonecrosis of the femoral head (ONFH), also known as avascular necrosis of the femoral head (AVN), is a common refractory disease in the field of orthopedics. There are two causes of femoral head necrosis. One is traumatic. The main pathogenic factors include femoral head and neck fracture, acetabular fracture, hip dislocation, severe hip sprain...

Claims

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Application Information

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Patent Type & AuthorityApplications(China)
IPC IPC(8): A61K35/644A23L21/20A23L33/10A23L33/15A61P19/08A61P1/00A61K31/196A61K31/4439A61K31/51
CPCA61K35/644A61K31/196A61K31/51A61K31/4439A61K9/0053A61P19/08A61P1/00A23L33/10A23L33/15A23L21/20A23V2002/00A61K2300/00A23V2250/7042A23V2200/306A23V2200/32
Inventor黄琛樊子东马琰杨爱彬时玉洁秦高茂王景霞袁辉杨晓彤
Owner黄琛