Chromatographic material and preparation method thereof, micro chromatographic column and coating method thereof, and micro gas chromatograph

Abstract

The invention provides a chromatographic material and a preparation method thereof, a micro chromatographic column and a coating method thereof, and a micro gas chromatograph. The preparation method of the chromatographic material comprises the following steps: adding a layer of stationary phase of a metal organic framework material on the surface of the magnetic particles to realize surface modification, and then cleaning and separating to take out the magnetic particles; and repeating the steps for N times, wherein N is a positive integer. According to the technical scheme of the invention, firstly, the surface of the chromatographic material is coated with a plurality of layers of metal organic framework materials as a stationary phase, so that the chromatographic material has a deeper internal structure and a larger specific surface area, and the chromatographic separation performance can be obviously improved; and secondly, as the carrier of the chromatographic material adopts the magnetic particles, the external magnetic force can be utilized to assist the separation operation and be fixed in the chromatographic column, and the method has the advantages of simplicity, convenience and feasibility.

Description

technical field [0001] The invention relates to a chromatographic material and a preparation method thereof, a micro chromatographic column and a coating method thereof and a micro gas chromatograph. Background technique [0002] With the development of Micro-Electro-Mechanical Systems (MEMS) technology, the miniaturization of instruments has become an inevitable trend. Gas chromatograph is an important instrument for separating and detecting mixed gases, and there are more and more researches on its miniaturization. Micro gas chromatographic column (μGC) is an important part of micro gas chromatograph, and there are more and more studies on the stationary phase used in it. [0003] At present, the most commonly used micro-gas chromatography stationary phase materials are polymer materials, such as polydimethylsiloxane, polyethylene glycol, polytrifluoropropylmethylsiloxane, polycyanoxydimethylsiloxane, etc. Generally, static or dynamic coating methods are used to modify t...

AI Technical Summary

Problems solved by technology

Although the above-mentioned stationary phase materials have a larger specific surface area, they are still spread on the inside of the microchromatogram, and the separation ability is limited.

Therefore, during gas separation, the contact area between gas molecules and the stationary phase is only the pore area of ​​the material inside the chromatographic column, so the separation effect of this method still needs to be improved

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