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Compound preparation for treating dysphagia, preparation method thereof and drug application ice rod

A technology for compound preparations and dysphagia, which can be applied to heating appliances for treatment, cooling appliances for treatment, medical preparations with non-active ingredients, etc., and can solve problems such as difficulty in taking medicine and the effect of easily inhaled patches. Achieve the effects of accelerating blood circulation, improving symptoms of swallowing disorders, and improving sensitivity

Active Publication Date: 2022-01-11
洛阳市中医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of this, the present invention aims to propose a compound preparation for the treatment of dysphagia, so as to overcome the clinical difficulties of patients with dysphagia in taking medicine, easy aspiration and poor patch effect.

Method used

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  • Compound preparation for treating dysphagia, preparation method thereof and drug application ice rod
  • Compound preparation for treating dysphagia, preparation method thereof and drug application ice rod
  • Compound preparation for treating dysphagia, preparation method thereof and drug application ice rod

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A compound preparation for treating dysphagia, comprising a drug extract and a matrix with a weight ratio of 1:8, the matrix is ​​glycerin gelatin, and the drug extract is made of the following raw materials: 5g of Pinellia chinensis, 16g of Shichangpu , Gastrodia elata 7g, Campanulaceae 11g, Citrus aurantium 5g, Asarum 2g, Mint 15g, Chuanxiong 12g, Borneol 6g, Aconite 4g, Fangfeng 20g, Boric acid 1g, Ginger 8g.

[0038] Prepared as follows:

[0039] S1. Weighing Pinellia, Shichangpu, Gastrodia elata, Campanulaceae, Citrus aurantium, Asarum, Chuanxiong, Aconite, Fangfeng, ginger, mint, add water to decoct twice, add 5 times for the first time (W / W) Deionized water decoction 2.5h, add 3 times deionized water decoction 1.5h for the second time, combine the deionized liquid, filter and concentrate to 1 / 6 of the original volume;

[0040] S2, add 95% (V / V) ethanol, adjust the amount of ethanol to 33% (V / V), let it stand, precipitate, take the supernatant and filter, concent...

Embodiment 2

[0043] A compound preparation for treating dysphagia, comprising a drug extract, a base, and potassium sorbate in a weight ratio of 1:15:0.1, the base is glycerin gelatin, and the drug extract is made of the following raw materials: Pinellia fragrans 9g, Shichangpu 11g, Gastrodia elata 11g, Campanulaceae 15g, Citrus aurantium 3g, Asarum 1g, Mint 25g, Chuanxiong 8g, Borneol 3g, Aconite 1g, Fangfeng 15g, Boric acid 3g, Ginger 15g.

[0044] Prepared as follows:

[0045] S1. Weighing method Pinellia, Shichangpu, Gastrodia elata, Campanulaceae, Citrus aurantium, Asarum, Chuanxiong, Aconite, Fangfeng, ginger, mint, add water to decoct twice, add 3 times for the first time (W / W) Deionize with deionized water for 4 hours, add 2 times (W / W) deionized water for the second time and decoct for 1.0 hours, combine the deionized liquid, filter and concentrate to 1 / 4 of the original volume;

[0046] S2, add 95% (V / V) ethanol, adjust the amount of ethanol to 35% (V / V), let it stand, precipita...

Embodiment 3

[0049] A compound preparation for treating dysphagia, comprising a drug extract, a base, and potassium sorbate in a weight ratio of 1:12:0.2, the base is glycerin gelatin, and the drug extract is made of the following raw materials: Pinellia fragrans 6g, Shichangpu 12g, Tianma 9g, Campanulaceae 12g, Citrus aurantium 4g, Asarum 1g, Mint 18g, Chuanxiong 9g, Borneolum 3g, Aconite 2g, Fangfeng 18g, Boric acid 3g, Ginger 12g.

[0050] Prepared as follows:

[0051] S1. Weighing Pinellia, Shichangpu, Gastrodia elata, Campanulaceae, Citrus aurantium, Asarum, Chuanxiong, Aconite, Fangfeng, ginger, mint, add water to decoct twice, add 4 times for the first time (W / W) Deionize for 3 hours, add 2.2 times (W / W) deionized water for 1.2 hours for the second time, combine the deionized liquid, filter and concentrate to 1 / 5 of the original volume;

[0052] S2, add 95% (V / V) ethanol, adjust the amount of ethanol to 34% (V / V), let it stand, precipitate, take the supernatant and filter, concentr...

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Abstract

The invention provides a compound preparation for treating dysphagia, a preparation method thereof and a drug application ice rod. The compound preparation comprises a drug extract and a matrix in a weight ratio of 1:(5-15). The drug extract is prepared from the following raw materials: 5-9 parts of rhizoma pinellinae praeparata, 11-16 parts of rhizoma acori graminei, 7-11 parts of rhizoma gastrodiae, 11-16 parts of radix platycodonis, 3-5 parts of fructus aurantii, 1-2 parts of herba asari, 15-25 parts of mint, 8-12 parts of rhizoma chuanxiong, 3-6 parts of borneol, 1-4 parts of rhizoma typhonii, 15-20 parts of radix saposhnikoviae, 1-3 parts of boric acid and 8-15 parts of fresh ginger. The compound preparation has reasonable compatibility, is convenient to take and capable of effectively avoiding aspiration by mistake and obviously relieving dysphagia after stroke, and is safe and reliable.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a compound preparation for treating dysphagia, a preparation method and a popsicle for administering medicine. Background technique [0002] Dysphagia refers to the process of inability to safely and effectively deliver food to the stomach due to damage to the structure and (or) function of the jaw, lips, tongue, soft palate, throat, esophagus and other organs; as the incidence of stroke increases and tends to be younger The incidence rate of this complication of dysphagia also reaches more than 30%. Long-term dysphagia can cause malnutrition, electrolyte imbalance, aspiration, induce aspiration pneumonia, and even cause suffocation and life-threatening, seriously affecting the treatment and rehabilitation of patients. With the gradual aging of our country, the rehabilitation treatment of dysphagia has been paid more and more attention by the Chinese people....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K47/42A61K47/36A61K47/38A61P11/04A61P1/02A61P25/00A61F7/12A61M31/00A61M37/00A61K31/045A61K33/22
CPCA61K36/8888A61K36/888A61K36/8988A61K36/346A61K36/752A61K36/268A61K36/534A61K36/236A61K31/045A61K36/238A61K33/22A61K36/9068A61K47/42A61K47/36A61K47/38A61P11/04A61P1/02A61P25/00A61F7/12A61M31/00A61M37/00A61K2236/331A61K2236/39A61K2236/53A61F2007/001A61M2037/0007A61M2210/065A61K2300/00A61M2210/005
Inventor 贾亚妹李亚利石利沙丁婷婷龚丹赵武朋
Owner 洛阳市中医院