Application of gene-enhanced immune cells in lung cancer
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- 青岛西凯生物技术有限公司
- Publication Date
- 2022-06-07
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Abstract
Description
technical field
[0001] The invention belongs to the technical field of immunology, in particular to the application of a gene-enhanced immune cell in lung cancer. Background technique
[0002] Natural killer cells (NK cells) are a major innate immune system lymphocyte in the body discovered by Rolf Kiessling and Ronald Heberman in the 1970s. Important member of the immune system. NK cells play an important role in resisting infection by foreign pathogens and in clearing deteriorating cancer cells. NK does not need antigen sensitization and MHC restriction in recognizing and killing tumor cells, and can secrete a variety of cytokines and chemokines to regulate immune response, so NK plays an important role in tumor cell immunotherapy.
[0003] Lung cancer is the most common malignant tumor in my country, and one of the malignant tumors with the highest morbidity and mortality in the world. According to statistics, about 1.8 million people are diagnosed with lung cancer eve...