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Process method for preparing biological product by using continuous flow centrifuge

A technology of biological products and process methods, which is applied in the direction of biological material sampling methods, biochemical equipment and methods, and specific-purpose bioreactors/fermenters, etc., which can solve product inhomogeneity, large number of personnel operations, and many opening times and other problems, to achieve the effect of reducing personnel operations, shortening operation time, and good airtightness

Active Publication Date: 2022-03-01
CHANGCHUN KEYGEN BIOLOGICAL PROD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional centrifuges have the disadvantages of large number of operations, many opening times, and uneven products.

Method used

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  • Process method for preparing biological product by using continuous flow centrifuge
  • Process method for preparing biological product by using continuous flow centrifuge
  • Process method for preparing biological product by using continuous flow centrifuge

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Embodiment Construction

[0046] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0047] It should be noted that when a component is referred to as being “fixed on” or “disposed on” another component, it may be directly on the other component or indirectly on the other component. When an element is referred to as being "connected to" another element, it can be directly or indirectly connected to the other element.

[0048] It is to be understood that the terms "length", "width", "top", "bottom", "front", "rear", "left", "right", "vertical", "horizontal", "top" , "bottom", "inner", "outer" and other indicated orientations or positional relations...

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Abstract

The invention discloses a process method for preparing a biological product by using a continuous flow centrifuge. The process method comprises the following steps: step 1, moving a cell factory framework to a working position of a six-axis sterile robot through a transfer trolley; 2, the cell factory framework is grabbed and placed through a six-axis sterile robot; step 3, adding liquid into the cell factory, discharging the liquid outwards from the cell factory, shaking, and stopping the action; and 4, preparing a culture stock solution through a one-time stirring system in combination with a continuous flow centrifuge. The robot is combined with the continuous flow centrifugal machine for use, operation flexibility is high, and the automation degree is high.

Description

technical field [0001] The invention belongs to the technical field of biological product preparation, and in particular relates to a process for preparing biological products using a continuous flow centrifuge. Background technique [0002] As a cell culture device, the cell factory can increase the culture area and improve the culture efficiency in a limited space. It is currently widely used in the fields of life sciences such as vaccines, monoclonal antibodies and cell extracts. Cell factories are mainly used for adherent cell culture, but can also be used for suspension cell culture. The cell factory has a variety of layers and specifications to meet the needs of laboratories and mass production, making it simple and easy to scale up from the laboratory scale without changing the kinetic conditions of cell growth. [0003] At present, the use of cell factories for the preparation of biological products generally adopts manual methods or traditional fixed turning machin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/00C12M1/36C12M1/02C12M1/00
CPCC12M23/52C12M23/14C12M41/48C12M29/00C12M23/48C12M27/02C12M33/10
Inventor 张夫坤顾建阳袁琳李晴范丽丽双慧周欣
Owner CHANGCHUN KEYGEN BIOLOGICAL PROD
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