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Oil-soluble natamycin preparation as well as preparation method and application thereof

A technology of natamycin and oil-soluble type, which is applied in the field of oil-soluble natamycin preparations and its preparation, can solve the problems of poor stability and difficulty in mixing the solution system uniformly, so as to improve stability, improve utilization efficiency and The effect of antibacterial effect

Pending Publication Date: 2022-03-22
SHANDONG FREDA BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the technical problems that natamycin is difficult to dissolve in edible oil, and the use of a dissolution system is difficult to mix uniformly and has poor stability, the present invention provides an oil-soluble natamycin preparation and its preparation method and application. The natamycin preparation can be miscible with edible oil in any proportion, and can form a relatively stable solution, which solves the problem that natamycin is almost insoluble in oil, and is easy to use

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  • Oil-soluble natamycin preparation as well as preparation method and application thereof
  • Oil-soluble natamycin preparation as well as preparation method and application thereof
  • Oil-soluble natamycin preparation as well as preparation method and application thereof

Examples

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Embodiment 1

[0029] An oil-soluble natamycin preparation, raw materials including particle diameter D90 is 10 μm of natamycin, propylene glycol (solvent), polysorbate 80 and zein, prepared according to the following method:

[0030] (1) Dissolve natamycin in the solvent at a ratio of 20g / l, add 12g / l polysorbate 80, and stir at 65°C and pH 8.0 until completely dissolved;

[0031] (2) After the solution is slowly cooled to room temperature, 10 g / l zein is added to obtain an oil-soluble natamycin preparation.

Embodiment 2

[0033] An oil-soluble natamycin preparation, the raw materials of which include natamycin with a particle size D90 of 10 μm, propylene glycol with a volume ratio of 2:1, glycerin mixture (solvent), polysorbate 80 and zein , prepared as follows:

[0034] (1) Dissolve natamycin in the solvent at a ratio of 22g / l, add 14g / l polysorbate 80, and stir at 60°C and pH 7.0 until completely dissolved;

[0035] (2) After the solution was slowly cooled to room temperature, 15 g / l zein was added to obtain an oil-soluble natamycin preparation.

[0036] Screening Example 1 Effect of Different Edible Alcohols on the Solubility of Natamycin

[0037] Take 90ml of propylene glycol, 90ml of glycerin, 90ml of propylene glycol and glycerol mixed solution with a volume ratio of 1:1, 90ml of propylene glycol and glycerol mixed solution with a volume ratio of 2:1, and 90ml of propylene glycol and glycerin with a volume ratio of 1:2. The triol mixed solution was dissolved in the above-mentioned 5 gro...

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Abstract

The invention relates to the technical field of food preservation and preservation, in particular to an oil-soluble natamycin preparation as well as a preparation method and application thereof. The preparation is prepared from the following raw materials: natamycin, edible alcohol, polysorbate 80 and zein, wherein the dosage ratio of the natamycin to the edible alcohol is 15-30g / l, the dosage ratio of the polysorbate 80 to the zein to the edible alcohol is 10-20g / l, and the dosage ratio of the zein to the edible alcohol is 5-25g / l. The preparation method comprises the following steps: (1) dissolving the natamycin in the edible alcohol, adding the polysorbate 80, and stirring and dissolving under the conditions that the temperature is 40-80 DEG C and the pH value is 4.0-9.0; (2) after the solution is cooled, adding zein to obtain an oil-soluble natamycin preparation; the oil-soluble natamycin preparation can be used for preservation and fresh-keeping of oil-containing food. The oil-soluble natamycin preparation can be mixed and dissolved with edible oil in any proportion to form a stable solution, the problem that natamycin is almost insoluble in oil is solved, and the oil-soluble natamycin preparation is convenient to use.

Description

technical field [0001] The invention relates to the technical field of food preservation and preservation, in particular to an oil-soluble natamycin preparation and its preparation method and application. Background technique [0002] Oily food itself is rich in nutrients, which is easy to cause the growth of microorganisms. Manufacturers always have to face the problem of excessive bacterial counts, coliforms, and mold. Among them, mold pollution is the most common, and it is an important factor that threatens food safety for consumers. For production Enterprises are the key to reputation and profit, and microbial control is the top priority in the production of oily food. [0003] Various chemical preservatives such as sodium diacetate, sodium dehydroacetate, potassium sorbate, propionate, etc. The use of it has played a great protective role in human life and normal production. However, with the improvement of people's awareness of the safety of chemically synthesized p...

Claims

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Application Information

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IPC IPC(8): A23B4/20A23B4/22A23C3/08A23L3/3463A21D15/00
CPCA23B4/20A23B4/22A23C3/08A23L3/34635A21D15/00A23V2002/00A23V2200/10A23V2250/5482
Inventor 张英华李海军郑德强周济源王兆兰张杰李艳艳
Owner SHANDONG FREDA BIOTECH