Method for preparing 5-substituted tetrazole compound and product obtained by method

A compound, tetrazolium technology, applied in the field of preparation of 5-substituted tetrazolium compounds, can solve the problems of complex post-processing operations, long reaction time, low reactivity, etc., achieve simplified separation and purification steps, and reduce reaction time , The effect of reducing the amount of catalyst
CN114478419APending Publication Date: 2022-05-13HUBEI ENG UNIV +1
0 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HUBEI ENG UNIV
Publication Date
2022-05-13

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention belongs to the field of organic synthesis, and particularly relates to a method for preparing a 5-substituted tetrazole compound and a product obtained by the method. According to the invention, the 5-substituted tetrazole compound can be prepared by using the chitosan immobilized zinc catalyst as a heterogeneous catalyst at room temperature in a water phase and an air atmosphere. The technical scheme has a series of advantages of mild conditions, environment friendliness, high reaction activity, convenience in product separation, capability of recycling the catalyst and the like.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of organic synthesis, and in particular relates to a method for preparing a 5-substituted tetrazole compound and a product obtained therefrom. Background technique

[0002] 5-Substituted tetrazole compounds are intermediates widely used in pharmaceutical production. For example, this type of compound can be applied to the production of losartan and candesartan drugs for the treatment of hypertension, diabetes and congestive heart failure. The 5-substituted tetrazole compound can also be used in the synthesis of a new generation of cephalosporin antibiotics and as an intermediate in the synthesis of antifungal drugs. In addition, the 5-substituted tetrazole compound can be used as a photosensitizer to improve the stability of the silver halide photosensitizer during storage.

[0003] The existing method for preparing 5-substituted tetrazole compounds mainly uses divalent zinc as a catalyst for heterogeneous catalysis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More