Traditional Chinese medicine composition for reducing blood pressure and blood fat and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of antihypertensive and lipid-lowering traditional Chinese medicine composition and preparation thereof, can solve the problems of poor appetite, side effects and the like, and achieve the effects of promoting gastric juice secretion, increasing gastric enzyme and dilating blood vessels

Pending Publication Date: 2022-06-28
ANHUI HUAIRENTANG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there are also side effects: more bowel sounds and diarrhea; occasional stomach pain, poor appetite, dry mouth, bitter mouth; individual asthma or liver pain

Method used

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  • Traditional Chinese medicine composition for reducing blood pressure and blood fat and preparation method thereof
  • Traditional Chinese medicine composition for reducing blood pressure and blood fat and preparation method thereof
  • Traditional Chinese medicine composition for reducing blood pressure and blood fat and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] The antihypertensive and lipid-lowering traditional Chinese medicine composition is composed of the following raw materials: 100 grams of Apocynum leaves, 100 grams of American ginseng, 90 grams of Rehmannia glutinosa, 100 grams of Astragalus, 90 grams of Gongju, 180 grams of fenugreek, 200 grams of Panax notoginseng, and hawthorn 80 grams, 130 grams of buckwheat, 200 grams of fried cassia seeds, 75 grams of green buckwheat, 90 grams of frost mulberry leaves.

[0046] Wherein, the superfine powders of the fried cassia seeds, mulberry leaves and Panax notoginseng that have been subjected to wall-breaking pulverization are selected, and the particle size after pulverization is not greater than 40 μm; the particle size after pulverization of the remaining raw materials is not greater than 1 mm.

[0047] Preparation:

[0048] (1) the preparation method of described fried cassia seed, frost mulberry leaf and Panax notoginseng superfine powder is as follows:

[0049] Take fr...

Embodiment 2 10

[0056] Embodiment 2 Dissolution rate test of Panax notoginseng powder

[0057] (1) Test method

[0058] Eight rabbits were selected to be fasted for 24 hours, two of them were used as blank control group, and were given normal saline by gavage, and two were given as ultrafine powder group, and the particle size was 10-30 μm with Panax notoginseng powder. Ordinary powder group, the notoginseng powder sold in the market was given to the stomach, and the particle size was about 1mm; 2 were combined powder group, mixed with Panax notoginseng ultrafine powder and the large particle size powder arrowroot powder of the present invention in a ratio of 1:1 gavage. The total weight of Panax notoginseng powder remained the same in the three groups of experiments.

[0059] The powder was prepared into a suspension of 11.8 g / L before gavage every day, and the dose was 0.18 mg / g by gavage, 3 times a day, with an interval of 6 hours, for one day. Within 6-14h after the last administration...

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Abstract

The traditional Chinese medicine composition is prepared from the following raw materials: folium apocyni veneti, American ginseng, radix rehmanniae recen, radix astragali, florists chrysanthemum, radix puerariae thomsonii, radix notoginseng, fructus crataegi, tartary buckwheat, fried semen cassiae, cyclocarya paliurus and 2-10% of frosted folium mori. Wherein the fried semen cassiae, the frosted mulberry leaves and the pseudo-ginseng are selected from superfine powder subjected to wall-breaking and crushing treatment, and the particle size of the crushed powder is not greater than 45 microns; the particle size of the rest crushed raw materials is not greater than 1mm. The composition is prepared from pure Chinese herbal medicines, the component compatibility is reasonable, the blood pressure and lipid lowering effect of the composition is obviously higher than that of a single component, and the blood pressure and lipid lowering effect plays an obvious superimposed effect of '1 + 1gt, 2'; through the compatibility effect of the hawthorn, the florists chrysanthemum and the like, the side effects of diarrhea, poor appetite, dry mouth, bitter taste and the like caused by the dogbane leaves are overcome.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a Chinese medicine composition for lowering blood pressure and lipids and a preparation method thereof. Background technique [0002] At present, the application of traditional Chinese medicine in my country has been more and more recognized by the international community. Its various medicinal materials have significant curative effects, and there are many drugs used to lower blood pressure and lipids. Apocynum leaves, kudzu, etc. [0003] Apocynum leaves, its gas is slight, the taste is light sweet, bitter, cool. Return to the liver meridian. Functions and Indications: Pinggan soothe the nerves, clearing heat and diuretic water. For liver-yang dizziness, palpitations, insomnia, edema and oliguria; hypertension, neurasthenia, nephritis and edema. The main components are rutin, catechin, isoquercetin, glutamic acid, alanine, valine, potassium chloride, et...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P3/06A61P9/12
CPCA61K36/24A61K36/258A61K36/804A61K36/481A61K36/287A61K36/488A61K36/734A61K36/70A61K36/482A61K36/52A61K36/605A61P9/12A61P3/06A61K2236/15A61K2300/00
Inventor 何家裕张国升朱来良江凤标赵红叶祖新宫夏婉朱雪梅
Owner ANHUI HUAIRENTANG PHARMA CO LTD
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