Aldehyde synthesis method

Abstract

The invention discloses a synthesis method of aldehyde. The synthesis method comprises the following steps: step 1, synthesis of an intermediate 1, step 2, synthesis of an intermediate 2, and step 3, synthesis of 4-acetoxy-2-methyl-2-butene-1-aldehyde. According to the synthesis method, the problems of high production cost, more three wastes and difficulty in treatment after the 4-acetoxy-2-methyl-2-butene-1-aldehyde is synthesized by the existing technical route are solved, a large amount of three wastes are reduced, the synthesis method is more environment-friendly, and meanwhile, the reaction risk is reduced.

Description

technical field [0001] The invention belongs to the field of organic chemical synthesis, in particular to a method for synthesizing an aldehyde. Background technique [0002] With the continuous development of science and technology, 4-acetoxy-2-methyl-2-butene-1-aldehyde (referred to as five-carbon aldehyde) is a C15+C5 route characterized by Wittig-Homer reaction to synthesize vitamin A ethyl Key intermediates of esters and carotenoids, the structural formula is as follows: [0003] [0004] The representative routes of main industrialization at present are: 1): take isoprene as starting material, first carry out addition reaction with hypochlorous acid generated by hydrolysis of trichloroisocyanuric acid to obtain 1-chloro-2-methyl-3- The mixture of buten-2-ol and 4-chloro-3-methyl-2-buten-1-ol is desolvated and then reacted with acetic anhydride through esterification and rearrangement of propenyl group to obtain 1-acetoxy-4 -Chloro-3-methyl-2-butene, and finally wi...

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Problems solved by technology

[0007] Aiming at the deficiencies in the prior art, the purpose of the present invention is to provide a synthetic method of aldehyde, which can solve the production cost after the prior art route synthesizes 4-acetoxy-2-methyl-2-butene-1-aldehyde. High, too much three wastes, difficult to deal with

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