Chinese medicinal composition for treating liver cancer

A technology for treating liver cancer and a composition, applied in the field of injection for treating liver cancer, can solve the problems of low purity, inoperable conventional treatment, intolerance and the like

Inactive Publication Date: 2005-12-21
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these treatments have many adverse reactions, and most of the patients are older, inoperable or intolerant to conventional treatments
At present, traditional Chinese medicines for the treatment of liver cancer are mainly oral drugs with large doses, low purity and slow curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] a) extraction of Scutellaria baicalensis:

[0085] Weigh 300g of Scutellaria baicalensis, add 10 times the amount of water, decoct three times, the first time for 2 hours, the second time for 1.5 hours, the third time for 1 hour, combine three decoctions, concentrate under reduced pressure to 5 times the amount of feed, Add concentrated hydrochloric acid to the concentrated solution at 80°C, adjust the acidification to PH2, and keep it warm at 80°C for 1 hour to precipitate the Scutellaria baicalensis, leave it at room temperature for 12 hours, discard the supernatant, filter the precipitate with suction, take the filter cake and add 10 times the amount of Make it into a suspension with water, dissolve it with 40% NaOH solution, adjust to PH7, add an equal amount of ethanol to dissolve Scutellaria baicalensis into sodium salt, filter out impurities, heat to 60°C, add concentrated hydrochloric acid to PH2, stir well, 60 Incubate at ℃ for 1 hour to precipitate baicalin, p...

Embodiment 2

[0094] Take 200g of Scutellaria baicalensis and 100g of Tianjihuang. The preparation method was the same as that in Example 1, and 14 g of Scutellaria baicalensis extract and 3.2 g of total flavonoids of Tianjihuang were obtained. Prepared as an injection of 140mg / 10ml / support. 2-3 sticks / day.

Embodiment 3

[0096] Take 300g of Scutellaria baicalensis and 200g of Tianjihuang. The preparation method was the same as that in Example 1, and 23.5 g of Scutellaria baicalensis extract and 6.3 g of total flavonoids of Tianjihuang were obtained. Prepared as an injection of 50mg / 10ml / support. 3-5 sticks / day.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating liver cancer, in particular to an injection made of traditional Chinese medicine for treating liver cancer. The traditional Chinese medicine composition of the invention is prepared from scutellaria baicalensis, Tianjihuang and pharmaceutically acceptable auxiliary materials and / or auxiliary agents. Applying the drug of the present invention to the treatment of primary liver cancer can significantly improve the patient's liver pain, abdominal distension, appetite loss, emaciation symptoms and liver function indicators, and improve the quality of life. The combined application with TACE can significantly reduce the AFP value and enhance the patient's liver function. Immunological function, reduce the toxic and side effects of interventional chemotherapy, stabilize the lesion, and prolong the survival time.

Description

(1) Technical field [0001] The invention relates to a traditional Chinese medicine composition for treating liver cancer, in particular to an injection made of traditional Chinese medicine for treating liver cancer. (2) Background technology [0002] Primary liver cancer is the third malignant tumor in my country. The mortality rate of liver cancer in urban areas is next to lung cancer and gastric cancer, ranking third, and in rural areas, it is second only to gastric cancer. At present, surgery is the main treatment for liver cancer. In addition, radiation therapy, interventional chemotherapy, local therapy, and biological immunotherapy can also be used. However, these treatments have many adverse reactions, and most of the patients are older, inoperable or intolerant to conventional treatments. At present, traditional Chinese medicines for the treatment of liver cancer are mainly oral medicines with large doses, low purity and slow curative effect. (3) Contents of the i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K9/20A61K9/48A61P35/00
Inventor 张素芹唐由君
Owner SHANDONG ACAD OF CHINESE MEDICINE
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