Method of increasing bone volume

A capacity and bone disease technology, applied in bone diseases, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve side effects and other problems
CN1269720AInactive Publication Date: 2000-10-11THE PROCTER & GAMBLE COMPANY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
THE PROCTER & GAMBLE COMPANY
Publication Date
2000-10-11
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

The present invention relates to novel methods of increasing bone volume comprising activating the osteoblastic protein kinase C / intracellular calcium pathways of a subject. This invention further relates to a method of treating or preventing bone disorders wherein activation occurs by the administration of a FP agonist.
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Description

technical field

[0001] The present invention relates to novel methods of increasing bone volume comprising activating the osteoblast protein kinase C / intracellular calcium pathway in a subject. The present invention also relates to a method of treating or preventing a bone disease, wherein the activation is produced by administering an agonist of FP. Background of the invention

[0002] In osteoporosis, an imbalance is created in the bone remodeling process, with bone resorption occurring faster than bone formation. Although in most individuals (both men and women) some degree of this imbalance develops as they age, it is more severe in younger people with osteoporosis, especially those with Among those patients with postmenopausal forms of osteoporosis. Accelerated bone loss may also be caused by medications (eg, corticosteroids), prolonged bed rest, disuse of extremities, and microgravity. The consequence of bone loss is the complete removal ...

Claims

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