Method and means for treating glomerulonephritis
A technology for glomerulonephritis and its use, applied in the field of treating glomerulonephritis
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[0018] A 52-year-old male suffered from nephrotic symptoms indicated by proteinuria and red blood cells in the urine in 1982. After renal biopsy and histological analysis of kidney tissue, he was diagnosed with IgA nephropathy. He was treated with various antihypertensive drugs, but proteinuria continued to increase and by 1990 he had developed renal insufficiency, and after that year he developed uremia which itself required dialysis. In 1993 he received a kidney from a deceased person. The transplanted kidney functioned satisfactorily for the first 24 months and the patient was treated with a systemically acting glucocorticoid substance (prednisolone) and an immunosuppressant drug (cyclosporine A) . In 1995, the first signs of nephropathy in transplanted kidneys were detected based on an increase in proteinuria as measured by changes in serum creatinine concentration and a decrease in renal function. After performing a renal biopsy of the graft and subsequent histological...
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