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Cough-stopping throat-clearing medicament made from chrysanthemum flower

A chrysanthemum and throat-clearing technology is applied in the field of chrysanthemum cough-relieving and throat-clearing preparations, and can solve the problems of unprovided extract preparations, low bioavailability, inconvenience in taking, etc., and achieves good solid dispersion, complete absorption, and biological High utilization effect

Inactive Publication Date: 2007-03-14
天津宝洁药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, people used it as a decoction or combined it with other Chinese medicinal materials to form a compound preparation, but it has the disadvantages of low bioavailability, large dosage, and inconvenient administration.
[0003] Recently, Tianjin Procter & Gamble Biological Products Co., Ltd. applied for the patent of "method and extract for extracting medicinal components of true chrysanthemum".

Method used

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  • Cough-stopping throat-clearing medicament made from chrysanthemum flower
  • Cough-stopping throat-clearing medicament made from chrysanthemum flower

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Example 1 Preparation of Chrysanthemum Zhike Qingyan Tablets

[0019] 1. Formula:

[0020] Chrysanthemum 5000g Starch 180g Sugar Powder 100g Sweetener 7g

[0021] Citric acid 7g Menthol 1g Magnesium stearate 2g

[0022] 1000 pieces

[0023] 2. Preparation method:

[0024] 1) Extraction of medicinal components of chrysanthemum: Weigh 5000g of chrysanthemum, add 12 times of 80% ethanol to the reaction tank, heat and reflux for extraction twice, each time for 2 hours, filter the extract to obtain the filtrate, concentrate under reduced pressure until alcohol-free taste, add 2 times the amount of water to make it into a suspension. Extract with hexyl acetate 4 times, 4000ml each time, combine the extracts, concentrate to dryness under reduced pressure, add 5000ml of 80% ethanol to dissolve it, concentrate under reduced pressure to a thick paste with a relative density of 1.25-1.30.

[0025] 2) Add 180g of starch, 100g of powdered sugar, 7g of sweetener, an...

Embodiment 2

[0028] Example 2 Preparation of Chrysanthemum Zhike Qingyan Granules

[0029] 1. Formula:

[0030] Chrysanthemum 5000g Dextrin 300g Sucrose powder 420g

[0031] Sweetener 7g Citric acid 7g Menthol 1g

[0032] 1000g

[0033] 2. Preparation method:

[0034] 1) Extraction of medicinal components of chrysanthemum: Weigh 5000g of chrysanthemum, add 12 times the amount of 80% ethanol to the reaction tank, heat and reflux for extraction twice, each time for 2 hours, filter the extract to obtain the filtrate, concentrate under reduced pressure until it has no alcohol smell , add 2 times the amount of water to make it a suspension. Extract with hexyl acetate 4 times, 4000ml each time, combine the extracts, concentrate to dryness under reduced pressure, add 5000ml of 80% ethanol to dissolve it, concentrate under reduced pressure to a thick paste with a relative density of 1.25-1.30.

[0035] 2) Take the thick paste extracted above, add 300g of dextrin, 420g of sucros...

Embodiment 3

[0037] Example 3 Preparation of Chrysanthemum Zhike Qingyan Capsules

[0038] 1. Formula:

[0039] Chrysanthemum 5000g starch 230g menthol 1g

[0040] 1000 capsules

[0041] 2. Preparation method:

[0042] 1) Extraction of medicinal components of chrysanthemum: Weigh 5000g of chrysanthemum, add 12 times the amount of 80% ethanol to the reaction tank, heat and reflux for extraction twice, each time for 2 hours, filter the extract to obtain the filtrate, concentrate under reduced pressure until it has no alcohol smell , add 2 times the amount of water to make it a suspension. Extract with hexyl acetate 4 times, 4000ml each time, combine the extracts, concentrate to dryness under reduced pressure, add 5000ml of 80% ethanol to dissolve it, concentrate under reduced pressure to a thick paste with a relative density of 1.25-1.30.

[0043] 2) Take the extracted thick paste, add 230g of starch and stir to make it evenly mixed, and then put it in a vacuum drying oven ...

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Abstract

Disclosed is a cough-stopping throat-clearing medicament made from chrysanthemum flower, characterized in that the ingredients of the medicament include, chrysanthemum flower 84-96%, adjuvant 2-17%. The invention also discloses the process for preparing the medicament which has the advantages of high biological availability and good curative effect.

Description

technical field [0001] The invention relates to a chrysanthemum medicament for relieving cough and clearing throat, in particular to a chrysanthemum medicament for relieving cough and clearing throat made from plant Chinese herbal medicine. Background technique [0002] Chrysanthemum is a traditional Chinese medicine with both medicine and food. It is mainly used for colds and wind-heat, headache, red eyes, sore throat, dizziness, tinnitus, boils and swollen toxins. In the past, people used it as a decoction or combined it with other Chinese medicinal materials to form a compound preparation, but it has the disadvantages of low bioavailability, large dosage and inconvenient taking. [0003] Recently, Tianjin Procter & Gamble Biological Products Co., Ltd. applied for the patent of "method and extract for extracting medicinal components of true chrysanthemum", which provided a method and extract for extracting medicinal components of chrysanthemum, but has not yet provided ext...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61K9/00A61P11/04A61P11/14A61K133/00
Inventor 高国强
Owner 天津宝洁药业有限公司
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