Sphingosine kinase and uses thereof

A technology of sphingosine kinase and dimethylsphingosine, applied in the field of treatment and/or preventive treatment of cancer, down-regulation of neoplastic cell growth, can solve the problem that has only just begun to be understood, and the signal has not been confirmed OK, etc.
CN1436241AInactive Publication Date: 2003-08-13MEDVET SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
MEDVET SCI
Publication Date
2003-08-13
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates generally to a method of modulating the growth of cells and, more particularly, to a method of down-regulating the growth of neoplastic cells. The present invention is useful, interalia, in the therapeutic and / or prophylactic treatment of cancers such as, but not limited to, solid cancers such as cancers of the colon, stomach, lung, brain, bone, oesophagus, pancreas, breast, ovary or uterus.
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Description

field of invention

[0001] The present invention relates generally to methods of modulating cell growth, and more particularly, the present invention relates to methods of down-regulating neoplastic cell growth. The present invention is particularly useful in the therapeutic and / or prophylactic treatment of cancers such as but not limited to solid cancers such as colon, stomach, lung, brain, bone, esophagus, pancreas, breast, ovary or uterus . Background of the invention

[0002] A bibliography of publications cited by the authors throughout this specification is collected at the end of this specification.

[0003] Reference to any prior art in this specification is not, and should not be taken as, an acknowledgment or any form of suggestion that such prior art forms part of the common general knowledge in Australia.

[0004] Sphingosine kinases are key regulatory enzymes in diverse cellular responses. Sphingosine-1-phosphate is known to be an important second messenger in...

Claims

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