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Irradiating production method of medicinal pig skin

A manufacturing method and pigskin technology, applied in medical science, prosthesis, etc., can solve problems such as sepsis and cross infection, and achieve the effects of low rejection, pain relief, and obvious antibacterial effect.

Inactive Publication Date: 2003-11-05
陈 庆裕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pigskin used in this therapy is all fresh pigskin. Although it has been treated with disinfectant, the positive rate of bacterial culture is still as high as 7-16%. After use, it will cause cross-infection and systemic sepsis

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0006] A method for manufacturing irradiated pigskin. The steps of the method are: a. Degreasing process: 30-60 kilograms of white pigs are killed alive, shaved, cleaned, peeled off the pigskin, and the subcutaneous fat is removed. Soak the pigskin in the degreasing solution for 30 minutes to 4 hours to remove the fat. The formula of the degreasing solution is: 5 kg of edible alkali, 3 kg of quicklime, and 92 kg of water; , cut long 40-50cm, wide 20-30cm, thick 0.3-0.9mm skin slices, then shave off the remaining hair and hair roots, then soak the pigskin skin slices in the drug solution for 8-14 hours, the formula of the drug solution is : Norfloxacin 0.3 kg, water 99.7 kg; c, the treated pigskin is irradiated with cobalt 60co, the irradiation dose is 25ky, the pigskin temperature is kept at 0-5°C during irradiation, and the pigskin is stored at -16 At -4°C, it can be used on burn wounds after taking it out to room temperature and rewarming.

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PUM

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Abstract

The production process of medicinal pig skin includes the following steps: soaking pig skin in degreasing solution, comprising soda, lime and water, for 0.5-4 hr to degrease; soaking the washed pig skin in medicine solution comprising Norfloxacin and water for 8-14 hr to medicate; and irradiating the treated pig skin with Co-60 ray. The pig skin thus treated is bacteria-free, has obvious antiseptic effect, less rejection and less protein and water loss, and may be used clinically.

Description

technical field [0001] The invention relates to a method for manufacturing medicinal pigskin, in particular to a method for manufacturing irradiated medicinal pigskin. Background technique [0002] In 1972, Ruijin Hospital used pigskin instead of allogeneic skin to treat third-degree burns. In 1980, the hospital officially reported that "63 cases of large area burns were treated by mixed transplantation of piglet skin and autologous skin". Currently the main biological dressing for salvage of extensive burns. This therapy is second only to allogeneic skin transplantation, but it is obviously better than various existing chemically synthesized artificial skins. The pigskin used in this therapy is all fresh pigskin. Although it has been treated with disinfectant, the positive rate of bacterial culture is still as high as 7-16%. After use, it will cause cross-infection and systemic sepsis. Contents of the invention [0003] The purpose of the present invention is to provide...

Claims

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Application Information

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IPC IPC(8): A61L27/60
Inventor 陈庆裕卢安球李国辉
Owner 陈 庆裕
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