Polyresistin dripping pill and its preparing method for immunodeficiency

A polyanti-alpha, drop-making technology, used in pill delivery, anti-tumor drugs, pharmaceutical formulations, etc., can solve the problems of accelerating red blood cell filtration speed and unclear

Inactive Publication Date: 2003-11-26
HONGYI SCI & TECH CO LTD NANCHANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The study also found that both polyantiin A and ginseng polysaccharide can accelerate the filtration rate of red blood cells, improve the deformability of red blood cells, thereby reducing blood viscosity and promoting the recovery of diseases such as atherosclerosis, but whether this is related to polyantiin A? The antitumor activity of the

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0036] formula:

[0037] Polyretin A 5g

[0038] Macrogol 6000 300g

[0039] Preparation method: Take polyethylene glycol 6000, heat it to melt, add polyantisine A, stir well, drop into simethicone oil under heat preservation condition, cool down to form pills, collect the dropped pills, and dry them to obtain the product.

example 2

[0041] formula:

[0042] Polyretin A 5g

[0043] Sodium stearate 30g

[0044] Insect Wax 5g

[0045] Preparation method: take sodium stearate and worm wax, heat to melt, add polycampus A, stir well, drop into 1% sulfuric acid aqueous solution under heat preservation condition, cool to form pills, collect the dripping pills, dry, and obtain.

example 3

[0047] formula:

[0048] Polyretin A 5g

[0049] Macrogol 4000 200g

[0050] Preparation method: take polyethylene glycol 4000, heat it to melt, add polyantigen A, stir well, drop into vegetable oil under heat preservation condition, cool down to form pills, collect the dripping pills, and dry them to obtain the product.

[0051] 4. Example 4

[0052] formula:

[0053] Polyretin A 5g

[0054] Glyceryl monostearate 150g

[0055] Preparation method: Take monoglyceride, heat it to melt, add polycamdine A, stir well, drop into 1% sulfuric acid aqueous solution under heat preservation condition and cool to form pellets, collect the pellets, dry to obtain.

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PUM

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Abstract

The present invention relates to polyresistin dripping pill and its preparation process. Type-A streptococcus hemolyticus strain is deeply cultured and extracted to obtain one kind of refined polysaccharide substance polyresistin with immunoactivity and antitumor activity and named alpha-mannose polypeptide chemically; polyresistin is added into molten matrix via stirring to form pill; and the pill is cooled in cooler and dried to prepare the polyresistin dripping pill. Preparing into dripping pill can raise the stability and biological utilization of the medicine for quick and lasting effect.

Description

technical field [0001] The invention relates to a pharmaceutical preparation of polyantisin A and its preparation method, in particular to a polysaccharide with immune activity and anti-tumor effect obtained by submerged culture, extraction and refining of Streptococcus A-hemolyticus strains The substance, its chemical name is α-mannose polypeptide dripping pill formulation and its preparation method. technical background [0002] Polyantisin A is a polysaccharide substance with immune activity and anti-tumor effect obtained by submerged culture, extraction and purification of A-hemolytic streptococcus strains, and its chemical composition is α-mannose polypeptide. It is the first new type of immune enhancer in my country. Since 1985, many domestic enterprises have produced it, and major breakthroughs have been made in its clinical application and pharmacological research. As early as 1991 and 1993, they reviewed the research progress and clinical application of polyclonal ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K38/16A61P35/00A61P37/02
Inventor 刘智许军钱进彭红刘孝乐
Owner HONGYI SCI & TECH CO LTD NANCHANG
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