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Method for separating effertive components of Chinese medicine by adopting membrane technique

A technology of active ingredients and membrane technology, applied in the field of extraction of active ingredients of traditional Chinese medicine, can solve the problems of increased production cost, high loss rate of active ingredients, high energy consumption, and achieves small loss of active ingredients, controllable quality standards, no secondary The effect of pollution

Inactive Publication Date: 2004-02-25
范兆科
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Problems solved by technology

In industrial production, the alcohol precipitation process is often used, and its active ingredient loss rate is high, sometimes as high as 60%. The use of a large amount of organic solvents not only increases the production cost, but also causes environmental pollution.
There are many and complicated steps in the extraction process, high energy consumption, and ineffective components cannot be removed to the maximum extent; the separation process is often operated at high temperature, causing a large amount of thermally sensitive active components to decompose, affecting the efficacy of the drug, and the quality standard is difficult to control. Features

Method used

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Examples

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Effect test

example 2

[0016] Take 5 kg of Radix isatidis, add water to decoct 3 times, combine the decoction, use a special stainless steel filter to cross-flow to remove medicinal residues and large particle impurities, use a microfiltration membrane with a pore size of 1 μm to remove small particles and macromolecular impurities, and use a 0.1 μm microfiltration membrane to remove small particles and macromolecular impurities. The filter membrane is used for primary separation, and the ultrafiltration membrane with a molecular weight cut-off of 10,000 is used for interception, and the second-stage separation is performed, and the nanofiltration membrane with a molecular weight cut-off of 200 is used for dehydration and concentration. Combine the active ingredients intercepted three times to obtain 2.1 kg of extract. Example 2 Membrane Technology Separation of Active Components of Gynostemma pentaphyllum

[0017] The whole herb of Gynostemma pentaphyllum has many functions such as anti-aging, anti...

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Abstract

The method for separating effective component of Chinese medicine by using membrane technology is characterized by that firstly, the liquid medicine can be filtered to remove impurity component, thenaccording to the molecular mass of effective component of Chinese medicine required for separation and extraction from liquid medicine, from large to small, the ultrafiltration membrane and nanofiltration membrane can be selected to make one stage or multistage, stage-to-stage entrapment of effective component of Chinese medicine so as to implement separation of effective component of Chinese medicine.

Description

technical field [0001] The invention relates to a method for extracting effective components of traditional Chinese medicine, in particular to a method for separating the effective components of traditional Chinese medicine by membrane technology. Background technique [0002] The traditional method of separating the active ingredients of traditional Chinese medicine is mainly to use organic solvent extraction first, and then use separation techniques such as chromatography and recrystallization to further improve the purity of the active ingredients, and finally make different preparations. In the extraction process of the above method, the organic solvent may interact with the active ingredient, causing the active ingredient to lose its original effect. In industrial production, the alcohol precipitation process is often used, and the loss rate of its active ingredients is high, sometimes as high as 60%. The use of a large amount of organic solvents not only increases the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07B63/00C07G99/00
Inventor 范兆科
Owner 范兆科
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