A medicine for external application in orthopedics, a production method and an application method thereof. The external application in orthopedics is composed of following raw materials by weight: 4-10 parts of rhubarb root and rhizome, 3-7 parts of amur cork-tree bark; phellodendron bark, 4-8 parts of scutellaria root, 2-8 parts of angelica root, 4-8 parts of garden burnet root, 5-7 parts of red peony root, 4-8 parts of tree peony bark, 4-8 parts of Cape jasmine fruit, 3-9 parts of Safflower, 3-7 parts of hirsute shiny bugleweed herb, 4-8 parts of Chinese angelica, 2-6 parts of combined spicebush root, 2-6 parts of nutgrass galingale rhizome, 3-9 parts of corydalis tuber, 3-9 parts of turmeric root tuber, 2-6 parts of Himalayan teasel root, and 2-6 parts of notoptetygium root. The raw materials are prepared to external application powder in traumatology, external application ointment in orthopedics or external application hot application powder in orthopedics. Three medicines are combined for treatment in different dosage forms according to different time sequences in early stage, middle stage and late stage of patient's condition of fracture. The invention can rapidly treat the fracture, having an effective rate of 100%; the medicine is flexible to administrate, has strong targeting function, is able to effectively achieve the fracture position and better plays effects, thus greatly reducing unfavourable reactions of medicine, preventing waste of the medicine resource and shortening period of healing of fracture.