Submicron powder Jinfang Baidu San normal temperature preparation method and special two-way airflow screen grader

A technology of Baidu powder and airflow sieve, which is applied in powder transportation, antiviral agents, pharmaceutical formulations, etc., can solve the problems of restricting the large-scale production of veterinary traditional Chinese medicine ultrafine powder, low bioavailability, and reduced pulverization efficiency. In large-scale industrial production, improve the rate of cell wall breaking, improve the effect of smell and taste

Active Publication Date: 2012-04-04
HENAN KANGXING PHARMA
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AI Technical Summary

Problems solved by technology

Jingfangbaidu powder currently used in poultry is mostly coarsely crushed powder, which has the disadvantages of large dose, coarse dosage form, poor appearance, etc., the active ingredients cannot be fully released, and the bioavailability is low, which seriously affects the quality of traditional Chinese medicine and clinical treatment effect. and cannot be directly added to drinking water
[0004] Traditional Chinese medicine ultrafine pulverization technology is an update and development of traditional pulverization technology. It not only retains the advantages of traditional Chinese medicine preparation technology, but also injects new vitality into the modern production of Chinese medicine. It has broad application prospects, but there are still some problems in actual production. Problems and problems: (1) Low production efficiency and high energy consumption are the main factors restricting the large-scale production of veterinary traditional Chinese medicine ultrafine powder
In the traditional closed-circuit crushing process of the rod mill, when most of the materials have reached the fineness requirement, there is always a small part of coarse powder mixed in it, and the crushing time needs to be greatly extended to further crush this part of the coarse powder to the required particle size , so that the crushing efficiency is reduced, and the energy consumption is greatly increased; (2) There is a difference in particle size uniformity of the material after classification in winnowing classification and classifying wheel classification, which greatly affects the production quality of Chinese veterinary drug compound superfine powder, especially in the application of animal When using drinking water, it is difficult to meet the usage requirements due to the existence of a small amount of unbroken cells
(3) In the traditional unidirectional airflow screening, when Chinese medicine is ultrafinely pulverized, as the particle size decreases, the surface area and surface energy of the material particles increase, the adsorption increases, the fluidity becomes poor, and it is easy to aggregate into large particles It is difficult to sieve and classify powders with a fineness of more than 200 mesh

Method used

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Embodiment Construction

[0055] like figure 1 , 2 Shown, the normal temperature preparation method of superfine powder Jingfangbaidu powder of the present invention, comprises the following steps:

[0056] Step 1: Select raw materials Nepeta Nepeta, Fangfeng, Notopterygium, Duhuo, Bupleurum, Peucedanum, Fructus Aurantii, Poria, Campanulaceae, Chuanxiong, Licorice, Mint, wash, dry naturally, and cut into 3-5cm long sections , by natural drying or drying to a moisture content of ≤10%;

[0057] In the second step, the above raw materials are respectively pulverized at a temperature of 20° C. to 25° C. to obtain coarse powder of traditional Chinese medicine with a particle size of 60 to 80 meshes;

[0058] The third step is to prepare the coarse powder of the above-mentioned raw materials according to Nepeta: Fangfeng: Notopterygium: Duhuo: Bupleurum: Peucedanum: Citrus aurantium: Poria cocos: Campanulaceae: Chuanxiong: Licorice: Mint = 9:6:5:5:6:5 :6:9:6:5:3:3 are mixed evenly in parts by weight;

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Abstract

The invention discloses a submicron powder Jinfang Baidu San normal temperature preparation method, which comprises the following steps that: herba schizonepetae, divaricate saposhnikovia root, notopterygium root, heracleum hemsleyanum michaux, radix bupleuri, peucedanum root, bitter orange, tuckahoe, balloon flower, rhizoma ligustici wallichii, liquorice and field mint are selected, dried and pulverized into coarse powder, the coarse powder is uniformly blended according to a proportion and is placed into a rod mill to be pulverized, the pulverized powder is blown into a special two-way airflow screen grader to pass through a 500-mesh sieve, the powder passing the sieve and having the granularity being less than or equal to 25 micrometers is conveyed into a cyclone collector to collect by airflow produced by a draught fan to obtain the submicron powder Jinfang Baidu San finished product; and powders which cannot pass through the 500-mesh sieve are collected by a funnel and are conveyed into the rod mill through a pipeline to be circularly pulverized. The submicron powder Jinfang Baidu San has advantages that: the entire preparation process is carried out under the normal temperature, no low temperature or other special additional conditions are required; the granularity of the prepared finished product medicine is less than or equal to 25 micrometers, so the cell wall breaking rate and the bioavailability are greatly improved; and the two-way airflow screen grader utilized in the method can simplify the preparation process of the submicron powder Jinfang Baidu San.

Description

technical field [0001] The invention relates to the field of veterinary drug preparations, in particular to a method for preparing superfine powder Jingfangbaidu powder at normal temperature; the invention also relates to a special two-way airflow sieving machine used in the method. Background technique [0002] Chinese herbal medicine has incomparable advantages over other chemically synthesized drugs in the prevention and treatment of diseases: high safety, less toxic and side effects, more active ingredients, less harmful residues, more targets of action, can play a combined effect, and is not easy to produce drug resistance It can regulate the body's immunity and enhance the body's disease resistance while antibacterial and antiviral. Under the background that countries around the world are increasingly emphasizing food safety and calling for green and ecological conditions, it is of great practical significance to promote the application of traditional Chinese veterinar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61K9/14B02C23/20A61P31/14
Inventor 于瑞张国祖温士杰冯永健曹凌杰
Owner HENAN KANGXING PHARMA
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