Preparation method for superfine bupleurum powder under normal temperature and special bidirectional airflow sieving machine

Abstract

The invention discloses a preparation method for superfine bupleurum powder under a normal temperature; the preparation method comprises the following steps of: firstly selecting radix bupleuri, radix scutellariae, pinellia, dangshen and liquorice, cleaning and cutting the radix bupleuri, the radix scutellariae, the pinellia, the dangshen and the liquorice into sections; drying the sections, and then respectively grinding the sections to obtain crude traditional Chinese medicine powders; uniformly mixing the crude traditional Chinese medicine powders according to proportions of 3:3:2:3:1, then placing the mixed crude traditional Chinese medicine powder in a rod mill to be ground, leading the ground powder to enter a special bidirectional airflow sieving machine through air supply to pass through a sieve with 500 meshes, sieving the ground powder to obtain powder with the particle size of less than or equal to 25 micrometers, conveying the powder into a cyclone material collecting device through air currents generated by a draught fan to be collected, thereby obtaining the superfine bupleurum powder finished product; and collecting and conveying the powder which is not sieved by the sieve with 500 meshes into the rod mill for secondary cyclic grinding. The preparation method has the advantages that the whole preparation process is carried out under the normal temperature, and low temperature or special auxiliary conditions are not needed; the particle size of the prepared medicine finished product is less than or equal to 25 micrometers, and the wall-broken rate of cells and the bioavailability are greatly increased; and the bidirectional airflow sieving machine adopted in the preparation method simplifies the preparation process of the superfine bupleurum powder.

Description

technical field [0001] The invention relates to the field of veterinary drug preparations, in particular to a normal-temperature preparation method of superfine powder Xiaochaihusan; the invention also relates to a special two-way airflow sieving machine used in the method. Background technique [0002] Chinese herbal medicine has incomparable advantages over other chemically synthesized drugs in the prevention and treatment of diseases: high safety, less toxic and side effects, more active ingredients, less harmful residues, more targets of action, can play a combined effect, and is not easy to produce drug resistance It can regulate the body's immunity and enhance the body's disease resistance while antibacterial and antiviral. Under the background that countries around the world are increasingly emphasizing food safety and calling for green and ecological conditions, it is of great practical significance to promote the application of traditional Chinese veterinary drugs f...

AI Technical Summary

Problems solved by technology

The currently used Xiaochaihu powder is mostly coarsely crushed powder, which has the disadvantages of large dosage (100-250g for horses and cattle, 30-60g for sheep and pigs), coarse dosage form (250-850 microns in particle size), poor appearance quality and palatability, etc. The active ingredients cannot be fully released, and the bioavailability is low, which seriously affects the quality of traditional Chinese medicine and clinical treatment effect

[0004] Traditional Chinese medicine ultrafine pulverization technology is an update and development of traditional pulverization technology. It not only retains the advantages of traditional Chinese medicine preparation technology, but also injects new vitality into the modern production of Chinese medicine. It has broad application prospects, but there are still some problems in actual production. Problems and problems: (1) Low production efficiency and high energy consumption are the main factors restricting the large-scale production of veterinary traditional Chinese medicine ultrafine powder

In the traditional closed-circuit crushing process of the rod mill, when most of the materials have reached the fineness requirement, there is always a small part of coarse powder mixed in it, and the crushing time needs to be greatly extended to further crush this part of the coarse powder to the required particle size , so that the crushing efficiency is reduced, and the energy consumption is greatly increased; (2) There is a difference in particle size uniformity of the material after classification in winnowing classification and classifying wheel classification, which greatly affects the production quality of Chinese veterinary drug compound superfine powder, especially in the application of animal When using drinking water, it is difficult to meet the usage requirements due to the existence of a small amount of unbroken cells

(3) In the traditional unidirectional airflow screening, when Chinese medicine is ultrafinely pulverized, as the particle size decreases, the surface area and surface energy of the material particles increase, the adsorption increases, the fluidity becomes poor, and it is easy to aggregate into large particles It is difficult to sieve and classify powders with a fineness of more than 200 mesh

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