A method of processing Chuanbei and Chuanbei preparation

Abstract

The invention provides a method for processing bulbus fritillariae cirrhosae and a bulbus fritillariae cirrhosae preparation. The method for processing the bulbus fritillariae cirrhosae comprises thefollowing steps: (1) cutting the bulbus fritillariae cirrhosae into slices or coarsely crushing the bulbus fritillariae cirrhosae, then adding an ethanol extracting solution of rosa davurica, and soaking for 1 to 2 hours under a room temperature, wherein the addition amount of the ethanol extracting solution of the rosa davurica enables the ethanol extracting solution to at least submerge the bulbus fritillariae cirrhosae; (2) drying the bulbus fritillariae cirrhosae at 70 to 100 DEG C until the water content thereof is lower than 8 percent; (3) superfinely grinding the dried bulbus fritillariae cirrhosae at -35 to -25 DEG C until the particle size of 95 percent or more bulbus fritillariae cirrhosae superfine powder is within a range of 400 to 600 meshes. By processing the bulbus fritillariae cirrhosae through the method disclosed by the invention, not only can brown stain be inhibited, the dissolving-out quantity of alkaloid and saponin be increased and a pharmaceutical effect be increased, but also the advantages of energy saving, low cost and high performance cost ratio are obtained.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine processing, in particular to a method for processing Chuanbei and a Chuanbei preparation. Background technique [0002] Chuanbei is the dried bulb of Liliaceae F.cirrhosa D.Don, Dark Purple Fritillaria F.unibracteata Hsiaoet K.C.Hsia, Gansu Fritillaria F.przewalskii Maxim. and Suosha Fritillaria F.delavayi Franch, belonging to my country Traditional precious Chinese medicinal materials. Starch is the main component of Chuanbei, accounting for about 40-60% of its total mass. The rest of the main components include cellulose, protein and fatty acids, etc., while the medicinal components of Chuanbei mainly include alkaloids, saponins and some terpenes. Classes and steroids. [0003] The book "Southern Yunnan Materia Medica" records that Chuan Fritillaria has the effects of clearing away heat and moistening the lungs, reducing phlegm and relieving cough. Modern pharmacological studies hav...

AI Technical Summary

Problems solved by technology

[0006] However, whether it is conventional ultrafine pulverization technology or low-temperature ultrafine pulverization technology, for different Chinese medicinal materials, the optimal process conditions for ultrafine pulverization vary greatly, and the specific processing effects are also very different. Some Chinese medicinal materials are even difficult to overcome due to Technical problems are not suitable for processing with the above-mentioned technologies

Reference 1 ("Research status and thinking of ultrafine pulverization of traditional Chinese medicine", Zhao Ruizhi, 2013 Symposium on Bioparticle Preparation Technology and Industrial Application Technology) records: below 20 μm, reducing the particle size of medicinal materials will increase the dissolution of anthraquinone in rhubarb for safflower and paeonol, superfine pulverization can not increase the dissolution of main components; superfine pulverization of ginseng can increase the dissolution of ginsenosides and polysaccharides, but there is no significant increase in curative effect

In addition, the physical and chemical properties of Chinese herbal medicines often change after ultra-micronization, which increases the difficulty in the later processing and use of medicines.

In addition, in addition to the characteristics of Chinese medicinal materials, ultra-fine pulverization technology, especially low-temperature super-temperature pulverization technology, consumes a lot of energy and high cost, which is also one of the difficulties encountered in applying the above technology to Chinese medicine processing

[0007] Therefore, in order to improve the rate of cell wall breaking and increase the dissolution of effective substances, it may be considered to process Chuanbei by low-temperature ultrafine pulverization, but the following technical problems need to be solved: (1) low-temperature ultrafine pulverization process conditions suitable for Chuanbei; 2) Before pulverization, the fritillary fritillary is prone to browning during the drying process; (3) After the fritillary fritillary is ultrafinely pulverized at low temperature, the physical and chemical properties may change, which is not conducive to subsequent processing and utilization

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