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Spray formulation of providone iodine

A technology of povidone-iodine and spray, which is applied in the directions of aerosol delivery, synthetic active ingredients of polymeric materials, digestive system, etc., can solve problems such as lack of

Inactive Publication Date: 2004-03-17
NANJING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is still a lack of formulations suitable for oral use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0103] Povidone-iodine 50g

[0104] Potassium iodate 1g

[0105] Potassium iodide 1.5g

[0106] Glycerin 200ml

[0107] Propylene glycol 100ml

[0108] Tween-80 1g

[0109] Menthol 2g

[0110] Add water to 1000ml

[0111] Stir and dissolve povidone-iodine with 1 / 3 of water to obtain solution I. Mix and stir glycerin and / or propylene glycol and 1 / 3 water to obtain solution II. Combine solution I and solution II and stir to obtain solution III. Separately dissolve potassium iodide and potassium iodate with a small amount of water and add, stir until uniform, add Tween-80, menthol, chocolate essence, add water to the total amount, and stir well. Serve in a container with a spout.

Embodiment 2

[0113] Povidone-iodine 50g

[0114] Potassium iodate 1g

[0115] Glycerin 300ml

[0116] Tween-80 1g

[0117] Menthol 2g

[0118] Chocolate essence 10g

[0119] Add water to 1000ml

[0120] The preparation method is the same as in Example 1.

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Abstract

The present invention discloses one kind of Povidone-iodine spraying agent, and features that the Povidone-iodine spraying agent consists of active component Povidone-iodine, potassium iodate and / or potassium iodide, glycerine and / or propylene glycol, corrective and water. It is stable in quality, has no irritation to skin and mucous membrane and is suitable for oral taking to prevent and treat bacterial, fungal and viral infection.

Description

1. Technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a spray containing povidone-iodine. 2. Technical background [0002] At present, the medication status of oral diseases and pharyngitis in our country is roughly as follows: oral surgery (such as tooth extraction, tooth correction, etc.) generally uses antibiotics to prevent wound infection, and the effect is good, but it is a systemic medication, which is not the most reasonable medication. Oral medicine, such as the treatment of inflammation such as oral ulcers, is mainly based on topical anti-inflammatory drugs, but there is a lack of topical drugs with ideal curative effect. Oral anti-inflammatory and antibacterial drugs are also used as the main treatment method for various infections of the throat position. [0003] Povidone iodine is a soluble complex formed by iodine and polyvinylpyrrolidone (PVP). Compared with iodine, it has the advantages of good water s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K31/80A61P1/02A61P11/04
Inventor 马雪华
Owner NANJING UNIV
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