Pyrithioxine hydrochloride freeze-dried power injection and its preparing method

A technology of pyrithione hydrochloride and freeze-dried powder injection, which is applied in the field of pyrithione hydrochloride freeze-dried powder for injection and preparation thereof

Inactive Publication Date: 2004-04-28
熊伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the drug went on the market, no inje...

Method used

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  • Pyrithioxine hydrochloride freeze-dried power injection and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] formula

[0011] Pyritinol hydrochloride: 200g

[0012] Mannitol: 100g

[0013] Water for injection: 1000ml

[0014] Freeze-dried into 1000 tubes

[0015] [Preparation method] According to the above preparation process.

Embodiment 2

[0017] formula

[0018] Pyritinol hydrochloride: 200g

[0019] Sodium chloride: 87g

[0020] Water for injection: 1000ml

[0021] Freeze-dried into 1000 tubes

[0022] [Preparation method] According to the above preparation process.

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Abstract

The present invention relates to a kind of freeze dried powder for intravenous injection with pyritinol hydrochloride as main component and its preparation process. The freeze dried powder for intravenous injection with pyritinol hydrochloride as main component is prepared by using water for injection or bacteria-free water as solvent, and mannitol and sodium chloride as supplementary material, and through freeze drying process. The present invention has no limitation of requiring bacteria-free material.

Description

technical field [0001] The invention is a freeze-dried powder injection mainly composed of pyrithione hydrochloride and a preparation method thereof. Background technique [0002] Pyritinol hydrochloride is a derivative of vitamin B6. It was developed and launched in Japan in 1962. It was synthesized and published in my country in 1972, and then the aseptic subpackaged preparation, pyrithione hydrochloride for injection, was launched on the market. Pyritinol hydrochloride for injection can improve brain function, promote the metabolism of glucose and amino acids in the brain, increase cerebral blood flow, promote brain cell nutrient metabolism, and improve cerebral hypoxia. It has been clinically confirmed by many hospitals: the drug has a good curative effect on traumatic brain injury and cerebral coma; it is particularly effective in promoting the recovery of consciousness; it has no obvious toxic and side effects and is safe to use. At the same time, the drug is also u...

Claims

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Application Information

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IPC IPC(8): A61K9/19A61K31/4415A61P43/00
Inventor 熊伟
Owner 熊伟
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