External used gel of Jiatishacin and its preparation

Abstract

An exterior-applied gel of Jiatishaxing is prepared through adding carbomer to glycerine, grinding, adding distilled water, grinding, adding the aqueous solution oftriethanolamine to obtain gel matrix, dissolving Jiatishaxing in distilled water, adding propanediol, stirring, slowly adding it to said gel matrix, adding distilled water and grinding.

Description

technical field [0001] The invention relates to an external drug for treating human skin and mucous membrane sensitive microbial infection and a preparation method thereof, in particular to a slow-release external gel for treating infections in dermatology, general surgery, urology and gynecology and a preparation method thereof. Background technique [0002] So far, the antibacterial drugs for external use for the treatment of human skin and mucous membrane microbial infectious diseases have few varieties and aging products. For example: "Chinese Pharmacopoeia" 2000 edition contains 14 antibacterial drugs for external use, such as erythromycin ointment, enoxacin ointment, compound clotrimazole ointment, compound neomycin ointment, aureomycin hydrochloride ointment, norfloxacin Ointment, silver sulfadiazine ointment, silver sulfadiazine cream, zinc sulfadiazine ointment, sulfadiazine ointment, etc. At present, the preferred topical quinolone antiba...

AI Technical Summary

Problems solved by technology

The fourth-generation quinolone antibacterial drugs, such as gatifloxacin, have not yet been developed and applied in clinical formulations for external use

There are 2nd and 3rd generation quinolones such as ciprofloxacin, ofloxacin, levofloxacin, norfloxacin and spafloxacin that have been developed and applied at home and abroad, but there is no 4th generation gel at present. Research Report on GFLX External Gel