Compound bergenin dripping pill and its preparing method

A technology of petracenin and compound rock, which is applied in the direction of pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of no reports, etc., and achieve the effect of increasing dissolution rate, obvious curative effect and good curative effect

Inactive Publication Date: 2005-05-18
贵阳高新瑞得科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no compound rock cabbage dropping

Method used

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Examples

Experimental program
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Effect test

Example Embodiment

[0018] Example Take 400g of mixed powder of Bergenin and Chlorpheniramine Maleate, add diluent, mix and mix into 600g of the excipient composed of polyethylene glycol 4000 and polyethylene glycol 6000 which are melted by heating and mix well; Then transfer the molten mixture into the dropping pill machine for dripping at a temperature of 75°C; drop the medicine into the liquid paraffin coolant and cool it at 12°C; use an absorbent cloth to absorb the coolant and select the pellets to obtain the compound rock Cabbage Supplement Pills; then packaged and shipped from the factory.

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PUM

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Abstract

The compound bergenin dripping pill as one medicine for treating chronic bronchitis consists of medicine and supplementary material. The medicine includes bergenin and chlorphenamine maleate and accounts for 3-40 wt%; and the supplementary material is polyglycol and accounts for 60-97 wt%. The preparation process of the compound bergenin dripping pill includes mixing bergenin and chlorphenamine maleate, dropping in a dripping pill machine into liquid paraffin as cooling agent, sucking cooling agent with sucking cloth and selecting pill. The compound bergenin dripping pill has well dispersed bergenin medicine, effectively raised medicine dissolving degree and thus excellent cough relieving and phlegm eliminating effect in treating chronic bronchitis.

Description

Technical field [0001] The invention belongs to a medicine for treating chronic bronchitis, in particular, belongs to a medicine using bergenin as an active ingredient, and also relates to a preparation method thereof. Background technique [0002] Medical practice has long proven: Bergenin in compound bergenin tablets composed of bergenin and chlorpheniramine maleate has good antitussive and expectorant effects on chronic bronchitis, and chlorpheniramine maleate has good antitussive and expectorant effects. Strong histamine H1 receptor blocking effect can alleviate other symptoms of the respiratory tract caused by allergies, and it also has a mild inhibitory effect on the central nervous system. However, bergenin has a small solubility in water, so its efficacy is affected to a certain extent. Although the compound bergenin tablets have certain curative effects, people are still exploring products with better curative effects to cure patients as soon as p...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K31/4402A61P11/00
Inventor 李向东卢顺林何斌
Owner 贵阳高新瑞得科技开发有限公司
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