Compound calcium replenishing injection

A technology for injection and calcium supplementation, which is applied in the fields of active ingredients of aluminum/calcium/magnesium, metabolic diseases, and active ingredients of boron compounds, etc. It can solve the problems of easy occurrence of calcium deposition diseases, low efficiency of calcium absorption by bones, and no quick effect.

Inactive Publication Date: 2005-06-29
关士林 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Ionic calcium injection has quick effect, no long-term effect and safety, can not prevent calcium deposition diseases, and the bone absorbs calcium inefficiently
[0004] Molecular calcium injection has long-term effect and safety, but no quick-acting effect, and cannot prevent calcium deposition diseases
Inefficient absorption of calcium by bones
[0005] The above two types of calcium injections are unilateral injections, which cannot overcome the above shortcomings. The common shortcomings are as follows:
[0006] (1) Quick-acting and long-acting are opposed, and the two cannot have both
[0007] (2) Quick-acting and safety are opposite, and both cannot have both
[0008] (3) prone to calcium deposition diseases
[0009] (4) Low efficiency of bone resorption of calcium

Method used

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Experimental program
Comparison scheme
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specific Embodiment approach

[0035] Specific implementation method: it includes two aspects: formula and operation process.

[0036] 1. Formula (content per bottle)

[0037] Calcium chloride (ionized calcium) 0.312mmol

[0038] Calcium gluconate (molecular calcium) 3.688mmol

[0039] Total Calcium 4.00mmol

[0040] Magnesium sulfate 1.152mmol

[0041] Sodium metasilicate 0.0893mmol

[0042] Sodium tetrasilicate 0.0347mmol

[0043] Vitamin K1 0.444μmol

[0044] Water 13.89mol

[0045] 2. Operation process

[0046] The amount of material used is 1000 times that of the recipe, increasing the accuracy of measurement. All pharmaceutical ingredients meet pharmaceutical quality requirements.

[0047] The preparation process of the compound calcium supplement injection is as follows: add the above-mentioned drug ingredients into a stainless steel reaction kettle, stir and dissolve until completely dissolved. The solution is a colorless transparent liquid without particles and precipitation. Then bottle...

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Abstract

The invention provides a compound calcium replenishing injection which is characterized in that, (1) utilizing the quick-effectiveness of the ionic calcium and the long-acting property of the big molecular diameter calcium, (2) utilizing the optimum calcium ion safety dosage of 0.312mmol, (3) appending calcium and magnesium simultaneously, (4) simultaneously charging calcium, magnesium, silicon, boron and vitamin K1. The injection can be applied for replenishing the calcium and treating several dozens of diseases.

Description

[0001] Technical field: western medicine pharmaceutical technology Background technique: [0002] Existing calcium supplement injections include ionic calcium injections and molecular calcium injections. Ionic calcium injection includes calcium chloride injection, and all calcium chloride in water and blood is composed of calcium ions (Ca ++ ) and chloride ions (Cl - ) form exists. Molecular calcium injection includes calcium gluconate, calcium fructonate, and calcium aspartate injection, most of which exist in molecular form in water and blood, and only a few molecules dissociate into Ca ++ . The performance is as follows: [0003] Ionic calcium injections have quick-acting effects, but no long-term effects and safety. They cannot prevent calcium deposition diseases, and the calcium absorption efficiency of bones is low. [0004] Molecular calcium injection has long-term effect and safety, but has no quick-acting effect and cannot prevent calcium deposition diseases. Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/19A61K33/06A61K33/12A61K33/22A61P3/02
Inventor 关士林杨世升石文渊刘井芬
Owner 关士林
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