Angelica root mistletoe granules and its preparation method

A kind of independent living and granule technology, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, block delivery, etc., and can solve problems such as vomiting, acceptance, and gastrointestinal irritation

Inactive Publication Date: 2005-08-10
唐德江
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be seen that this dosage form is a preparation with a relatively high alcohol content. The disadvantage of a large amount of ethanol is that in addition to increasing the cost of the product, the more important thing is that it stimulates the gastrointestinal tract. After taking it, you often feel uncomfortable and even cause vomiting. It is not easy to be accepted by patients, which affects the normal performance of the curative effect. People who are allergic to ethanol, or the elderly, children, and patients who are forbidden to drink alcohol such as fever, vomiting, and gastrointestinal ulcers are also unsuitable for taking it, which limits the scope of treatment objects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0177] Weigh raw materials according to the following ratio (kg)

[0178] Duhuo 9, Sangjisheng 6, Gentiana 6, Fangfeng 6, Asarum 6, Angelica 6, Paeoniae Alba 6, Rhizoma Chuanxiong 6, Rehmannia glutinosa 6, Eucommia 6, Achyranthes bidentata 6, Codonopsis 6, Poria 6, Licorice 6, Guizhi 6 .

[0179] The preparation method is as follows:

[0180] Add 6 times the amount of water to extract the volatile oil of the above fifteen flavors, Duhuo, Fangfeng, Asarum, Angelica, Chuanxiong, and Guizhi; Carry out percolation after soaking by roll method for 30 hours, collect 6 times the amount of percolation liquid, recover ethanol under reduced pressure and concentrate to a thick paste with a relative density of 1.20 (40-50°C). Take another appropriate amount of starch, make granules with thick paste, dry, add volatile oil, mix well, and get ready.

Embodiment 2

[0182] Weigh raw materials according to the following ratio (kg)

[0183] Duhuo 14, Sangjisheng 8, Gentiana chinensis 8, Fangfeng 8, Asarum 8, Angelica 8, Paeoniae Alba 8, Rhizoma Chuanxiong 8, Rehmannia glutinosa 8, Eucommia 8, Achyranthes chinensis 8, Codonopsis 8, Poria 8, Licorice 8, Guizhi 8 .

[0184] The preparation method is as follows:

[0185] Add 8 times the amount of water to extract the volatile oils of the above fifteen flavors, lovage, wind, asarum, angelica, chuanxiong, and cassia twig; use 70% ethanol as the solvent for the dregs and the other nine flavors, and use the infiltration under the liquid extract and the extract. Percolation was carried out after 48 hours of roll immersion, 7 times the amount of percolation liquid was collected, ethanol was recovered under reduced pressure and concentrated to a thick paste with a relative density of 1.30 (40-50°C). Take another appropriate amount of ethyl cellulose water dispersion, make granules with thick paste, ...

Embodiment 3

[0187] Weigh raw materials according to the following ratio (kg)

[0188] Duhuo 6, Sangjisheng 5, Gentiana quinquefolium 5, Fangfeng 5, Asarum 5, Angelica 5, Paeoniae Alba 5, Rhizoma Chuanxiong 5, Rehmannia glutinosa 5, Eucommia 5, Achyranthes bidentata 5, Codonopsis 5, Poria 5, Licorice 5, Guizhi 5 .

[0189] The preparation method is as follows:

[0190]Add 10 times the amount of water to extract the volatile oils of the above fifteen flavors, Duhuo, Fangfeng, Asarum, Angelica, Chuanxiong, and Guizhi; Carry out percolation after soaking by roll method for 60 hours, collect 8 times the percolation liquid, recover ethanol under reduced pressure and concentrate to a thick paste with a relative density of 1.40 (40-50°C). Separately take appropriate amount of starch and ethyl cellulose water dispersion, make granules with thick paste, dry, add volatile oil, mix well, and get ready.

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PUM

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Abstract

A Chinese medicine in the form of particles for treating rheumatism is prepared from 15 Chinese-medicinal materials including Chinese angelica root, white peony root, Chuan-xiong rhizome, liquorice root, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a medicine for treating rheumatic arthralgia. Specifically, the Chinese patent medicine is prepared from Chinese herbal medicine, and the invention also relates to a preparation method of the medicine. Background technique [0002] Rheumatism is a kind of disease that is caused by various reasons and mainly manifests as pain in bones, joints, muscles and their affiliated tissues. Poor, seriously endangering human health. [0003] At present, the American Rheumatology Association (ARA) divides rheumatism into 10 categories, which have been adopted by the World Health Organization. These diseases mainly include rheumatoid arthritis, rheumatoid arthritis, proliferative arthritis, and polyarterial nodosa Inflammation, etc., especially rheumatism and rheumatoid arthritis, osteoarthritis, gout, ankylosing, spondylitis and other diseases with high incidence, poor prognosis and high disability rate. [0004] Now, there are non-hormo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61P19/02A61P19/06A61P29/00
Inventor 唐德江陈犁
Owner 唐德江
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