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Medicament for treating gonarthromeningitis and preparation technology thereof

A technology for synovitis and knee joint, which is applied in the field of medicine for treating knee joint synovitis and its preparation technology, and can solve the problems of low market share

Inactive Publication Date: 2010-03-17
HENAN LUOZHENG PHARMA FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently, there is only one type of Chinese patent medicine for knee synovitis on the market, "Huamoyan Granules", and the market share is relatively low

Method used

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  • Medicament for treating gonarthromeningitis and preparation technology thereof
  • Medicament for treating gonarthromeningitis and preparation technology thereof
  • Medicament for treating gonarthromeningitis and preparation technology thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0129] The medicine of this embodiment is made of the following raw materials in parts by weight: Astragalus 1500, Gentiana 600, Angelica 500, Dipsacus 500, Cortex Moutan 500, Bupleurum 500, Curcuma 600, Sangjisheng 500, Mianzi 600, Sichuan Achyranthes bidentata 300, raw licorice 300, dextrin 100, aspartame 1.5, milk flavor 2.5, mint flavor 4.5.

[0130] The preparation method of this example is: decoct the above-mentioned components with 10 times the amount of water for 3 times, each time for 1 hour, combine the decoction, filter, concentrate the filtrate to a relative density of 1.18 (80°C), and cool to 40°C When adding ethanol to make the alcohol content reach 50%, fully stir, let stand for 24h, and filter the supernatant; After that, combine the ethanol liquid, recover the ethanol and concentrate to a relative density of 1.08 (65°C), add dextrin and aspartame, mix evenly, and spray dry to obtain dry extract powder, add 2.5g of milk essence and 4.5g of mint essence , mix ...

Embodiment 2

[0132] The medicine of this embodiment is made of the following raw materials in parts by weight: Astragalus 1800, Gentiana 950, Angelica 650, Dipsacus 650, Cortex Moutan 650, Bupleurum 650, Curcuma 950, Sangjisheng 650, Mianzi 950, Sichuan Achyranthes bidentata 500, raw licorice 500, dextrin 120, aspartame 2.0, milk flavor 3.0, mint flavor 5.5.

[0133] The preparation method of this example is: decoct the above-mentioned components with 10 times the amount of water for 3 times, each time for 1 hour, combine the decoction, filter, concentrate the filtrate to a relative density of 1.22 (80°C), and cool to 40°C When adding ethanol to make the alcohol content reach 50%, fully stir, let stand for 24h, and filter the supernatant; After that, the ethanol solution was combined, the ethanol was recovered and concentrated to a relative density of 1.14 (65°C), added dextrin and aspartame, mixed evenly, spray-dried to obtain dry extract powder, added milk essence and mint essence, mixe...

Embodiment 3

[0135] The medicine of this embodiment is made of the following raw materials in parts by weight: Astragalus 1600, Gentiana 850, Angelica 650, Dipsacus 600, Cortex Moutan 600, Bupleurum 600, Curcuma 850, Sangjisheng 600, Mianzi 850, Sichuan Achyranthes bidentata 400, raw licorice 400, dextrin 110, aspartame 1.8, milk flavor 2.7, mint flavor 5.0.

[0136] The preparation method of this example is: decoct the above-mentioned components with 10 times the amount of water for 3 times, each time for 1 hour, combine the decoction, filter, concentrate the filtrate to a relative density of 1.20 (80°C), and cool to 40°C When adding ethanol to make the alcohol content reach 50%, fully stir, let stand for 24h, and filter the supernatant; After that, the ethanol solution was combined, the ethanol was recovered and concentrated to a relative density of 1.10 (65°C), added dextrin and aspartame, mixed evenly, spray-dried to obtain dry extract powder, added milk essence and mint essence, mixe...

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Abstract

The invention discloses a medicament for treating gonarthromeningitis, which is prepared from the following raw materials in portion by weight: 1,500 to 1,800 portions of radix astragali, 600 to 950 portions of largeleaf gentian root, 500 to 650 portions of Chinese angelica, 500 to 650 portions of himalayan teasel root, 500 to 650 portions of tree peony bark, 500 to 650 portions of Chinese thorowax root, 600 to 950 portions of turmeric, 500 to 650 portions of Chinese taxillus twig, 600 to 950 portions of rhizoma dioscoreae septemlobae, 300 to 500 portions of medicinal cyathula root, 300 to 500portions of raw licorice, 100 to 120 portions of dextrin, 1.5 to 2.0 portions of aspartame, 2.5 to 3.0 portions of milk flavor, and 4.5 to 5.5 portions of mint essence. Preparation technology comprises the steps of: adding 10 times of water into the components to decoct for 3 times, merging and filtering decoction solutions, condensing a filtrate until the relative density is between 1.18 and 1.22 (80 DEG C), adding ethanol into the filtrate when the filtrate is cooled to 40 DEG C to ensure that the ethanol content reaches 50 percent, fully stirring the obtained solution, standing the obtained solution, and filtering to obtain a supernatant fluid; and adding 50 percent ethanol which is one half of a first ethanol precipitation solution into residue, stirring the obtained solution evenly,standing the solution, filtering the solution, merging ethanol solutions, recovering the ethanol, condensing the solution until the relative density is between 1.08 and 1.14 (65 DEG C), adding the dextrin and the aspartame into the solution to mix evenly, performing spray drying to obtain dry extract powder, and adding the milk flavor and the mint essence into the dry extract powder to mix evenlyto obtain particles. The medicament is used for treating diseases such as knee joint swelling, pain and function restriction caused by the gonarthromeningitis, and has the functions of benefiting qi.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and mainly relates to a medicine for treating knee joint synovitis and a preparation process thereof. Background technique [0002] Knee synovitis is a non-infectious inflammation with knee joint swelling, pain, and effusion as the main symptoms, which can be divided into acute traumatic synovitis, chronic synovitis and degenerative synovitis. Knee synovitis is a common and frequently-occurring disease. Among the middle-aged and elderly people, 85% of the knee joints will have varying degrees of X-ray changes. The incidence is high and affects the quality of life. According to the changing characteristics of the human disease spectrum, the age of onset of the disease tends to decrease. Currently, there is only one type of Chinese patent medicine for knee synovitis on the market, "Synovitis Granules", and its market share is relatively low. [0003] Guo Weihuai,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/16A61K47/40A61P19/02A61P29/00
Inventor 杜志谦袁秀荣王战朝杜天信刘培建江海肖
Owner HENAN LUOZHENG PHARMA FACTORY
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