Verification sample of liquid ability containing niacinamide, and preparation method

A technology of proficiency testing and nicotinamide, applied in the preparation of test samples, etc., to achieve the effect of credible test results

Inactive Publication Date: 2005-11-16
秦成 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The new data search shows that the test samples used for proficiency testing activities between toxicology laboratories have not been reported at home and abroad

Method used

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  • Verification sample of liquid ability containing niacinamide, and preparation method
  • Verification sample of liquid ability containing niacinamide, and preparation method
  • Verification sample of liquid ability containing niacinamide, and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Prepare 100mL liquid proficiency test sample containing nicotinamide

[0019] According to the properties of food additive-nicotinamide and the requirements of toxicology experiments, the solvent for preparing the proficiency testing liquid sample is 0.9% sodium chloride saline.

[0020] 1. Firstly, according to the animal experiments, it is determined that the highest concentration of the samples in this group is 177.78mg / mL, and the lowest concentration is 94.48mg / mL.

[0021] 2. Determine that the group of samples is divided into 7 samples according to the amount-effect relationship presented in the animal experiment, and the ratio coefficient between the samples is 0.9, and each sample is prepared according to the ratio relationship, specifically using the "low ratio dilution method" "Preparation solution:

[0022] 2.1 Weigh 177.78g of pure medicinal nicotinamide powder, add 1000mL of 0.9% sodium chloride saline, mix well, dilute to volume, and mix again, this solu...

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Abstract

An ability verification sample of liquid containing niacinamide is composed of 4 - 9 liquid samples as their concentration being presented in equal ratio relation. The equal ratio coefficient between liquid samples is 0.60 - 0.95 and samples solvent is 0.9 % sodium chloride - normal saline. The method for preparing the samples is also disclosed.

Description

technical field [0001] The invention relates to the technical field of toxicology proficiency testing, in particular to a liquid proficiency testing sample containing a single food additive component and a preparation method for the sample. Background technique [0002] Niacinamide, namely vitamin PP: promotes the health of the digestive system and relieves gastrointestinal disorders; promotes skin health; prevents and relieves severe migraines; promotes blood circulation and lowers blood pressure; relieves diarrhea; relieves discomfort of Meniere's disease ; Enable the body to make full use of food to increase energy; treat inflammation of the mouth and lips, prevent bad breath; reduce cholesterol and triglycerides. Because of its above-mentioned multiple effects, it is widely used in medicine, feed and health food, but some people will have adverse reactions, such as dizziness, nausea, upper abdominal discomfort, etc., and the daily intake of nicotinamide by the human body...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/28
Inventor 秦成宋慧君郑江
Owner 秦成
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