Collagen-chitin and silicon rubber bilayer skin regeneration support and its preparation method

A technology of skin regeneration and chitosan, applied in medical science, prosthesis, etc., can solve the problem of insufficient supply of autologous skin, achieve good elasticity and clinical ease of operation, promote healing, and prevent bacterial invasion
CN1785444AInactive Publication Date: 2006-06-14ZHEJIANG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ZHEJIANG UNIV
Publication Date
2006-06-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

A dual-layer scaffold for the skin regeneration is composed of a porous collagen-chitosan scaffold for inducing the migration, reproduction and differentiation of cells and the generation of dermal tissue and a silica rubber film as temporary epidermal layer for preventing the volatilization of water and the intrusion of bacteria. It has high biocompatibility, controllable degradation speed and excellent wound repairing power.
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Description

technical field

[0001] The invention relates to a double-layer skin regeneration support and a preparation method thereof. Specifically, it relates to a collagen-chitosan and silicon rubber double-layer skin regeneration support and a preparation method thereof. Background technique

[0002] Burns or ulcers of the skin are very common surgical diseases, such as wounds in various accidents and wars, and skin ulcers caused by self-diseases such as diabetes. Skin defects can affect the patient's appearance in mild cases, and in severe cases can cause infection or a large loss of electrolytes and water, leading to the death of the patient. Although skin tissue has a strong regenerative ability, for a large area of ​​full-thickness skin defect, the skin loses its ability to spontaneously regenerate. The key to the treatment of full-thickness skin defects is to seal the wound as early as possible, so as to reduce the consumption of the body, the disturbance of the internal envir...

Claims

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