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Oral taking tablets of Roxatidine Acetate Hydrochloride

A kind of technology of roxatidine hydrochloride acetate and oral tablet, applied in the field of preparing the tablet

Inactive Publication Date: 2006-07-05
北京德众万全医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As we all know, injection will inevitably bring pain, which is not easy for drug users to accept.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] The present invention is described below in conjunction with embodiment, but not limited to following embodiment:

[0023] components

[0024] Mix component 1 with components 3, 4, and 5, then add Eudragit RL-30D to the mixture of the above components to make wet granules and dry them. Mix the dried granules with components 6, 7, and 8 evenly, and press them into tablets with a diameter of 10 mm. The tablet has mint flavor and no bad taste when chewed in the oral cavity, and is easy to be accepted by users.

[0025] components

[0026] Mix component 1 with components 3, 4, 5, and 6, then add Eudragit RS-30D to the mixture of the above components to make wet granules and dry them. Mix the dry granules with components 7 and 8 evenly, and press them into tablets with a diameter of 11 mm. The tablet has a lemon taste and no bad taste in the oral cavity, and is easy to be accepted by users.

[0027] components

[0028] Mix component 1 with co...

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PUM

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Abstract

An oral tablet of roxatidine hydrochloride acetate with agreeable taste features that the acrylic resin kind of polymers as adhesive and the essence are used as part of its raw materials.

Description

technical field [0001] The invention relates to an oral tablet of roxatidine hydrochloride acetate whose mouthfeel is easy to be accepted by patients, and a method for preparing the tablet. Background technique [0002] Roxatidine acetate hydrochloride can inhibit human gastric acid secretion, so it has a positive effect on the treatment of human digestive tract diseases. However, like many tintins, this compound has an unpleasant bitter taste in the mouth. [0003] For some patients, such as children or some elderly people, swallowing medicines is often not easily accepted or realized. Patient compliance can be greatly improved if maltaste active ingredients are formulated into palatable tablets. Therefore, masking the unpleasant taste of active ingredients with therapeutic effects is a primary concern when designing tablets such as chewable or buccal tablets. [0004] U.S. Patent 5275823 discloses a kind of chewable tablet, is made of histamine H2 receptor antagonist, a...

Claims

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Application Information

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IPC IPC(8): A61K31/4453A61K9/20A61P1/04
Inventor 张宝隆李颖寰
Owner 北京德众万全医药科技有限公司
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