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Pharmaceutical composition for treating nose disease and its preparation method

The technology of a composition and medicine is applied in the pharmaceutical composition of chronic rhinitis, in the treatment of acute field, and can solve problems such as treating the symptoms but not the root cause.

Active Publication Date: 2006-07-26
SINOPHARM GRP DEZHONG (FOSHAN) PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

They all have the defects of treating the symptoms but not the root cause in different degrees

Method used

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  • Pharmaceutical composition for treating nose disease and its preparation method
  • Pharmaceutical composition for treating nose disease and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] [embodiment 1] preparation of spray

[0039] 1. Weigh each raw material

[0040] Ephedrine Hydrochloride 5g Baicalin 20g

[0041] borneol 1g magnolia oil 2g

[0042] Honeysuckle 300g

[0043] Second, the arrangement of medicinal materials

[0044] Honeysuckle: Pick out impurities and wash medicinal materials.

[0045] Three, the preparation of honeysuckle extract

[0046] Take 300g of honeysuckle, decoct twice with water, filter, concentrate the filtrate to a relative density of about 1.0-1.2, add 1kg of ethanol to purify, and concentrate the purified solution to obtain the product.

[0047] 4. Solution preparation

[0048] Add water to baicalin, stir well, add appropriate amount of sodium hydroxide solution to dissolve, adjust the pH value to 6.5-8.5, filter the honeysuckle extract, and set aside. Add water to ephedrine hydrochloride to dissolve it for later use. Dissolve borneol and magnolia oil in ethanol, mix with the above baicalin solution, honeysuckle fil...

Embodiment 2

[0049] [embodiment 2] preparation of pill

[0050] 1. Weigh each raw material

[0051] Ephedrine Hydrochloride 2g Baicalin 7g

[0052] Borneol 0.4g Magnolia oil 0.8g

[0053] Honeysuckle 100g

[0054] Second, the arrangement of medicinal materials

[0055] Honeysuckle: Pick out impurities and wash medicinal materials.

[0056] 3. Preparation of honeysuckle extract or honeysuckle dry extract powder

[0057] Take 100g of honeysuckle, decoct twice with water, filter, concentrate the filtrate to a relative density of about 1.0-1.2, add about 1kg of ethanol, purify, concentrate the purified solution or spray dry it.

[0058] 4. Pan Pills

[0059]The honeysuckle extract is diluted with water, filtered, and the filtrate is set aside. Mix ephedrine hydrochloride, baicalin and 3.75g carboxymethyl starch sodium to make fine powder. Put a small amount of fine powder into the vat, start the pellet making vat, start to spray a small amount of honeysuckle extract, stir continuously ...

Embodiment 3

[0065] [Example 3] Preparation of tablet

[0066] 1. Weigh each raw material

[0067] Ephedrine Hydrochloride 15g Baicalin 60g

[0068] borneol 3g magnolia oil 5.5g

[0069] Honeysuckle 900g

[0070] Second, the arrangement of medicinal materials

[0071] Honeysuckle: Pick out impurities and wash medicinal materials.

[0072] Three, the preparation of honeysuckle dry extract powder

[0073] Take 900g of honeysuckle, decoct twice with water, filter, concentrate the filtrate to a relative density of about 1.0-1.2, and spray dry to obtain honeysuckle dry extract powder.

[0074] 4. Preparation of tablets

[0075] The honeysuckle dry extract powder, ephedrine hydrochloride, borneol, magnolia oil, baicalin and appropriate amount of pregelatinized starch are made into granules, pressed into tablets, and coated with film.

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Abstract

The invention discloses a pharmaceutical composition for treating nasal diseases, which is prepared from the following raw material medicaments: ephedrine hydrochloride, glycoside of baikal skullcap root, lily magnolia oil, boneol and honeysuckle flower. The pharmaceutical composition can be made into any clinically acceptable preparations through conventional methods in the prior art, preferably nasal drops, aerosols and sprays.

Description

technical field [0001] The invention relates to a new pharmaceutical composition for treating nasal diseases and a preparation method thereof, in particular to a pharmaceutical composition for treating acute and chronic rhinitis mainly made of Chinese herbal medicine. Background technique [0002] Rhinology disease is clinical common disease, frequently-occurring disease. According to the theory of traditional Chinese medicine, the nose is the gateway for air to come in and go out, it controls the sense of smell, helps pronunciation, and belongs to the lung system. The nose is the orifice outside the lung. "Suwen·Yin and Yang Yingxiang Dalun" says: "The lung dominates the nose... the orifice is the nose", pointing out the relationship between the lung and the nose. "Su Wen Pulse Du Pian" said: "Lung Qi flows through the nose, and when the lungs are in harmony, the nose can know the fragrance and smell." "Lingshu Benshen Chapter" says: "Lung qi deficiency will cause nasal c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/355A61K9/00A61P11/02A61K31/045A61K31/17
Inventor 崔方祥杨雄辉
Owner SINOPHARM GRP DEZHONG (FOSHAN) PHARM CO LTD
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